Volume 18, Number 5—May 2012
Dispatch
Coxsackievirus A21, Enterovirus 68, and Acute Respiratory Tract Infection, China
Zichun Xiang, Richard Gonzalez, Zhong Wang, Lili Ren, Yan Xiao, Jianguo Li, Yongjun Li, Guy Vernet, Gláucia Paranhos-Baccalà, Qi Jin, and Jianwei Wang
Table 2
Demographic and clinical characteristics of sampled population with human enterovirus infections, People’s Republic of China, August 2006–April 2010*
| Characteristic | No. (%) persons |
||
|---|---|---|---|
| Coxsackievirus A21, n = 34 | Enterovirus 68, n = 13 | Any human enterovirus, n = 130 | |
| Sex | |||
| M | 18 (52.9) | 7 (53.8) | 69 (53.1) |
| F | 16 (47.1) | 6 (46.2) | 61 (46.9) |
| Signs and symptoms | |||
| Pharyngeal congestion | 34 (100) | 13 (100.0) | 128 (98.5) |
| Headache | 27 (79.4) | 10 (76.9) | 104 (80.0) |
| Myalgia | 25 (73.5) | 9 (69.2) | 93 (71.5) |
| Chills | 25 (73.5) | 7 (53.8) | 89 (68.5) |
| Sore throat | 23 (67.6) | 7 (53.8) | 82 (63.1) |
| Rhinorrhea | 17 (50.0) | 5 (38.5) | 50 (38.5) |
| Sneezing | 14 (41.2) | 3 (23.1) | 44 (33.8) |
| Cough | 7 (20.6) | 3 (23.1) | 19 (14.6) |
| Swelling of tonsils | 6 (17.6) | 1 (7.7) | 16 (12.3) |
| Expectoration | 4 (11.8) | 0 | 6 (4.6) |
| Rigors | 1 (2.9) | 1 (7.7) | 4 (3.1) |
| Preliminary clinical diagnosis | |||
| Upper respiratory tract infection | 33 (97.1) | 13 (100.0) | 126 (96.9) |
| Tonsillitis | 0 | 0 | 2 (1.5) |
| Pulmonary infection | 0 | 0 | 1 (0.8) |
| Other viruses co-detected | 1 (2.9)† | 1 (7.7)† | 8 (6.2)‡ |
*Median age (range) of patients with coxsackievirus A21 infection, 22 (15–67) y; median age (range) of patients with enterovirus V68 infection, 34 (18–67) y; median age (range) of patients with any enterovirus infection, 27.5 (15–70) y. Median age of patients with coxsackievirus A21 infection was younger than that of patients with other human enterovirus infections (χ2 14.7; p<0.01).
†Influenza virus A (n = 1).
‡Influenza virus A (n = 2), parainfluenza virus 3 (n = 2), rhinovirus (n = 2), metapneumovirus (n = 1), coronavirus OC43 (n = 1).
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