Volume 18, Number 6—June 2012
CME ACTIVITY - Research
Pretransplant Fecal Carriage of Extended-Spectrum β-Lactamase–producing Enterobacteriaceae and Infection after Liver Transplant, France
Frédéric Bert
, Béatrice Larroque, Catherine Paugam-Burtz, Federica Dondero, François Durand, Estelle Marcon, Jacques Belghiti, Richard Moreau, and Marie-Hélène Nicolas-Chanoine
, Béatrice Larroque, Catherine Paugam-Burtz, Federica Dondero, François Durand, Estelle Marcon, Jacques Belghiti, Richard Moreau, and Marie-Hélène Nicolas-Chanoine
Table 5
Risk factors for ESBLE infection after liver transplant, by stepwise logistic regression analysis, France, January 2001–April 2010*
| Variable† | OR (95% CI) | p value |
|---|---|---|
| Pretransplant ESBLE fecal carriage | 18.4 (7.1–47.5) | <0.0001 |
| MELD score >25 | 2.9 (1.4–6.2) | 0.0053 |
| Return to surgery | 2.7 (1.3–5.9) | 0.011 |
*ESBLE, extended-spectrum β-lactamase-producing Enterobacteriaceae; OR, odds ratio; MELD, Model for End-stage Liver Disease.
†Other factors initially in the model were hepatocellular carcinoma, acute liver failure, pretransplant ICU stay >48h, hospital stay >10 d in the 6 mo before transplant, spontaneous bacterial peritonitis in the 6 mo before transplant, red blood cells transfused, and posttransplant acute renal failure.
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