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Volume 18, Number 7—July 2012
Letter

Ebola Virus Antibodies in Fruit Bats, Ghana, West Africa

David T.S. HaymanComments to Author , Meng Yu, Gary Crameri, Lin-Fa Wang, Richard Suu-Ire, James L.N. Wood, and Andrew A. Cunningham
Author affiliations: University of Cambridge, Cambridge, UK (D.T.S. Hayman, J.L.N. Wood); Zoological Society of London, London, UK (D.T.S. Hayman, A.A. Cunningham); Animal Health and Veterinary Laboratories Agency, Weybridge, UK (D.T.S. Hayman); Colorado State University, Fort Collins, CO, USA (D.T.S. Hayman); CSIRO Livestock Industries, Geelong, Victoria, Australia (M. Yu, G. Crameri, L.-F. Wang); and Ghana Forestry Commission, Accra, Ghana (R. Suu-Ire)

Main Article

Table

ZEBOV- and REBOV-specific results of ELISA and Western blot analysis of serum from Ebola virus–positive fruit bats, Ghana*

Location, date, fruit bat species Sex Age ELISA OD (endpoint titer dilution)
Western blot†
REBOV ZEBOV REBOV ZEBOV
Sagyimase
May 29, 2007
Epomops franqueti F A 0.11 (1:50) 0.53 (1:200) − +
E. franqueti F SI 0.08 (1:50) 0.62 (1:100) + +
Hypsignathus monstrosus F A 0.12 (1:50) 1.08 (1:200) + +
H. monstrosus F SI 1.11 (1:200) 0.17 (1:50) + −
H. monstrosus F A 0.15 0.71 − −
H. monstrosus‡ M SI 0.05 0.11 − −
May 30, 2007
E. franqueti F A 0.1§ 0.53§ − +
Adoagyiri
May 31, 2007
Epomophorus gambianus M A 0.59 0.67 − −
E. franqueti§ F A 0.05 0.16 − −
E. gambianus F A 0.19 0.55 − −
E. gambianus F A 0.13 (1:50) 1.24 (1:800) − +
E. gambianus F SI 0.65 (1:200) 0.36 (1:50) + −
Oyibi
June 2, 2007
E. gambianus M A 0.51 0.63 − −
Negative control (RAB691/d0) 0.19 0.27
Positive control (RAB691/EBOV-N) 1.39 1.42 + +

*ZEBOV, Zaire Ebola virus; REBOV, Reston Ebola virus; OD, optical density; A, adult; SI, sexually immature.
†Only serum samples with ZEBOV- or REBOV- positive ELISA results (optical density >0.50) were tested.
‡Negative-control field serum samples.
§Additional serum was not available for endpoint titer dilution determination.

Main Article

Page created: June 14, 2012
Page updated: June 14, 2012
Page reviewed: June 14, 2012
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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