Volume 18, Number 7—July 2012
Dispatch
Seroconversion to Seasonal Influenza Viruses after A(H1N1)pdm09 Virus Infection, Quebec, Canada
Mariana Baz, Jesse Papenburg, Marie-Eve Hamelin, Manale Ouakki, Danuta M. Skowronski, Gaston De Serres, and Guy Boivin
Table
Clinical features and microneutralization antibody titers against influenza A(H1N1)pdm09 and seasonal influenza A viruses of persons who seroconverted to >2 influenza viruses, Quebec City, Quebec, Canada, 2009*
| Participant no./age, y | RT-PCR for A(H1N1) pdm09 | Titers, acute phase/convalescent phase (-fold increase) |
||||||
|---|---|---|---|---|---|---|---|---|
| Symptoms |
A/Quebec/147023/ 2009; A(H1N1)pdm09 | A/Brisbane/59/ 2007 (H1N1) | A/New Caledonia/ 99 (H1N1) | A/Panama/2007/99 (H3N2) | ||||
| ARI | ILI | |||||||
| 39A/7 | + | + | + | <10/160 (16) | <10/320 (32) | <10/160 (16) | 320/160 (0) | |
| 39C/11 | + | + | + | <10/40 (4) | 10/160 (16) | <10/40 (4) | 2,560/2,560 (0) | |
| 49A/28 | + | + | + | <10/160 (16) | 40/160 (4) | <10/20 (2) | 320/320 (0) | |
| 49B/23 | + | + | + | <10/640 (64) | <10/160 (16) | 40/160 (4) | 40/40 (0) | |
| 55F/7 | + | + | + | <10/40 (4) | 10/40 (4) | 20/80 (4) | 10/10 (0) | |
| 16C/7 | + | + | + | <10/80 (8) | 160/320 (2) | 40/160 (4) | 80/80 (0) | |
| 56A/12 | + | + | + | <10/40 (4) | 80/320 (4) | 40/80 (2) | 2,560/2,560 (0) | |
| 65B/40 | + | + | + | <10/320 (32) | <10/20 (2) | 10/40 (4) | 320/320 (0) | |
| 03E/17 | + | + | + | <10/80 (8) | 40/80 (2) | 160/160 (0) | 640/5120 (8) | |
| 10B/14 | + | + | + | <10/80 (8) | 20/20 (0) | 80/320 (4) | 640/640 (0) | |
| 11C/61† | + | + | + | <10/1,280 (128) | 40/160 (4) | 160/160 (0) | 320/1,280 (4) | |
| 44B/9 | + | + | + | <10/<80 (8) | 1,280/640 (0) | 1,280/1,280 (0) | 160/640 (4) | |
| 44C/44 | – | + | – | <10/20 (2) | 10/80 (8) | 80/80 (0) | 160/640 (4) | |
| 58A/13 | + | + | + | <10/80 (8) | <10/20 (2) | 10/20 (2) | 1,280/5,120 (4) | |
| 58B/43 | + | + | – | <10/160 (16) | <10/10 (0) | <10/<10 (0) | 20/160 (8) | |
*RT-PCR, reverse transcription PCR; ARI, acute respiratory illness (i.e., presence of ≥2 of the following signs/symptoms: fever [≥37.8°C] or feverishness, cough, sore throat, or rhinorrhea); ILI, influenza-like illness (i.e., fever and cough and/or sore throat); +, positive; –, negative.
†Received seasonal vaccine in 2008–09.
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Page updated: June 13, 2012
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