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Volume 18, Number 9—September 2012
Research

Trends in Meningococcal Disease in the United States Military, 1971–2010

Michael P. BroderickComments to Author , Dennis J. Faix, Christian J. Hansen, and Patrick J. Blair
Author affiliations: Naval Health Research Center, San Diego, California, USA

Main Article

Figure 1

Timeline showing 100 years of meningococcal disease incidence in the US population compared with members of the US Army (A) and effects of introduction of meningococcal vaccines (B; years in which the vaccine types were introduced into the military indicated by arrows). Rates are unadjusted for age matching. Data for the US Army and the general population for 1910–1946 from Brundage and Zollinger (2). General population data for 1967–1977 from Brundage and Zollinger (2) and for 1978–2009 from th

Figure 1. . . . Timeline showing 100 years of meningococcal disease incidence in the US population compared with members of the US Army (A) and effects of introduction of meningococcal vaccines (B; years in which the vaccine types were introduced into the military indicated by arrows). Rates are unadjusted for age matching. Data for the US Army and the general population for 1910–1946 from Brundage and Zollinger (2). General population data for 1967–1977 from Brundage and Zollinger (2) and for 1978–2009 from the Centers for Disease Control and Prevention (3). US Army data for 1964–1998 from Brundage et al. (1), 1999–2010 from personal communication with the Armed Forces Health Surveillance Center, and 2006–2009 from Naval Health Research Center Meningococcal Disease Surveillance. The incidence in the Army from 1982–1989 of 2.1 cases per 100,000 person-years was deduced from in Brundage et al. (1) by using the percentage of each military division’s percentage contribution to the total active-duty military populations during 1982–1989, with each year’s percentages estimated from those of the 1990–1992 average. These percentages were stable within ±2 percentage points during 1990–2006. Poly, polysaccharide; C, Neisseria meningitidis serogroup C; A, N. meningitidis serogroup A; quad, quadravalent (N. meningitidis serogroups A, C, W-135, and Y); conjug, conjugate.

Main Article

References
  1. Brundage  JF, Ryan  MA, Feighner  BH, Erdtmann  FJ. Meningococcal disease among United States military service members in relation to routine uses of vaccines with different serogroup-specific components, 1964–1998. Clin Infect Dis. 2002;35:1376–81. DOIPubMedGoogle Scholar
  2. Brundage  JF, Zollinger  WD. Evolution of meningococcal disease epidemiology in the US Army. In: Vedros NA, editor. Evolution of meningococcal disease, vol. I. Boca Raton (FL): CRC Press; 1987. p. 1885–1921.
  3. Centers for Disease Control and Prevention. Active Bacterial Core Surveillance (ABCs) report, Emerging Infections Program Network, Neisseria meningitidis, 2009. 2010 [cited 2012 Jun 12]. http://www.cdc.gov/abcs/reports-findings/survreports/mening09.pdf
  4. Armed Forces Epidemiological Board Infectious Diseases Control Subcommittee. Vaccines in the military: a Department of Defense–wide review of vaccine policy and practice. A report of the Infectious Diseases Control Subcommittee of the Armed Forces Epidemiological Board. Falls Church (VA): The Board; 1999.
  5. Centers for Disease Control and Prevention. Meningococcal disease and college students. Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep. 2000;49(RR-7):13–20.PubMedGoogle Scholar
  6. Centers for Disease Control and Prevention. Prevention and control of meningococcal disease. Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep. 2010;49(RR-7):1–10.
  7. Rubertone  MV, Brundage  JF. The Defense Medical Surveillance System and the Department of Defense Serum Repository: glimpses of the future of public health surveillance. Am J Public Health. 2002;92:1900–4. DOIPubMedGoogle Scholar
  8. Breslow  NE, Day  NE. Statistical methods in cancer research. Volume II—the design and analysis of cohort studies. Lyon (France): International Agency for Research on Cancer; 1987.
  9. Young  LS, LaForce  FM, Head  JJ, Feeley  JC, Bennett  JV. A simultaneous outbreak of meningococcal and influenza infections. N Engl J Med. 1972;287:5–9. DOIPubMedGoogle Scholar
  10. Moore  PS, Hierholzer  J, DeWitt  W, Gouan  K, Djore  D, Lippeveld  T, Respiratory viruses and mycoplasma as cofactors for epidemic group A meningococcal meningitis. JAMA. 1990;264:1271–5. DOIPubMedGoogle Scholar
  11. Rosenstein  NE, Perkins  BA, Stephens  DS, Popovic  T, Hughes  JM. Meningococcal disease. N Engl J Med. 2001;344:1378–88. DOIPubMedGoogle Scholar
  12. Crum  N, Chapman  FA, Russell  KL, Hale  BR. The many faces of meningococcal disease: a case series and review of presentations and treatment options. Infect Dis Clin Pract. 2005;13:5–9. DOIGoogle Scholar
  13. Artenstein  MS, Rust  JH Jr, Hunter  DH, Lamson  TH, Buescher  EL. Acute respiratory disease and meningococcal infection in army recruits. JAMA. 1967;201:1004–7. DOIPubMedGoogle Scholar
  14. Keyserling  HL, Pollard  AJ, DeTora  LM, Gilmet  GP. Experience with MCV-4, a meningococcal, diphtheria toxoid conjugate vaccine against serogroups A, C, Y and W-135. Expert Rev Vaccines. 2006;5:445–59. DOIPubMedGoogle Scholar
  15. Auckland  C, Gray  S, Borrow  R, Andrews  N, Goldblatt  D, Ramsay  M, Clinical and immunologic risk factors for meningococcal C conjugate vaccine failure in the United Kingdom. J Infect Dis. 2006;194:1745–52. DOIPubMedGoogle Scholar
  16. Centers for Disease Control and Prevention. Updated recommendations for use of meningococcal conjugate vaccines—Advisory Committee on Immunization Practices (ACIP), 2010. MMWR Morb Mortal Wkly Rep. 2011;60:72–6.PubMedGoogle Scholar
  17. Bilukha  OO, Rosenstein  N. Prevention and control of meningococcal disease: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Morb Mortal Wkly Rep. 2005;54(RR-7):1–21.PubMedGoogle Scholar
  18. Bruce  MG, Rosenstein  NE, Capparella  JM, Shutt  KA, Perkins  BA, Collins  M. Risk factors for meningococcal disease in college students. JAMA. 2001;286:688–93. DOIPubMedGoogle Scholar

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