Volume 19, Number 1—January 2013
Dispatch
Seropositivity for Influenza A(H1N1)pdm09 Virus among Frontline Health Care Personnel
Kumar Alagappan, Robert A. Silverman
, Kathy Hancock, Mary Frances Ward, Meredith Akerman, Fatimah S. Dawood, Alicia Branch, Sandra De Cicco, Evelene Steward-Clark, Megan McCullough, Karen Tenner, and Jacqueline M. Katz
, Kathy Hancock, Mary Frances Ward, Meredith Akerman, Fatimah S. Dawood, Alicia Branch, Sandra De Cicco, Evelene Steward-Clark, Megan McCullough, Karen Tenner, and Jacqueline M. Katz
Table 2
Univariate and multivariate analysis of risk indicators for seropositivity for influenza A(H1N1)pdm09 virus among 340 study participants*
| Characteristic | No. (%) seropositive, n= 65 | No. (%) seronegative, n = 257 | Crude OR (95% CI) | Adjusted OR (95% CI) |
|---|---|---|---|---|
| Sex | ||||
|
M |
22 (33.9) | 116 (42.2) | Referent | NA |
|
F |
43 (66.2) | 159 (57.8) | 1.41 (0.80–2.49) | NA |
| Age, y | ||||
|
<30 |
15 (23.1) | 41 (14.9) | 2.01 (0.60–6.81) | NA |
|
30–40 |
20 (30.8) | 65 (23.6) | 1.57 (0.48–5.15) | NA |
|
41–50 |
14 (21.5) | 67 (24.4) | 1.15 (0.34–3.86) | NA |
|
51–60 |
12 (18.5) | 79 (28.7) | 0.84 (0.25–2.85) | NA |
|
>60 |
4 (6.2) | 22 (8.0) | Referent | NA |
| Age, y (dichotomized) | ||||
|
<60 |
61 (93.9) | 253 (92.0) | 1.32 (0.44–3.96) | NA |
|
>60 |
4 (6.2) | 22 (8.0) | Referent | NA |
| Received seasonal influenza vaccine during 2008 or 2009 | 61 (93.9) | 252 (91.6) | 1.30 (0.43–3.91) | NA |
| Contact with person with suspected A(H1N1)pdm09 virus infection | 13 (20.0) | 49 (17.8) | 1.17 (0.59–2.31) | NA |
| Children <18 y of age at home | 36 (55.4) | 104 (37.8) | 1.96 (1.13–3.40) | 1.96 (1.13–3.40) |
| Occupation | ||||
|
Non-HCP |
24 (36.9) | 123 (44.7) | Referent | NA |
|
HCP |
41 (63.1) | 152 (55.3) | 1.35 (0.77–2.36) | NA |
| ILI† during spring–summer 2009 | 15 (23.1) | 19 (6.9) | 3.97 (1.85–8.49) | NA |
| ARI‡ during spring–summer 2009 | 25 (38.5) | 53 (19.3) | 2.55 (1.41–4.60) | NA |
*OR, odds ratio; NA, not applicable; HCP, health care personnel; ILI, influenza-like illness; ARI, acute respiratory illness. ILI and ARI were not included in the adjusted logistic regression model because they did not reflect risk for exposure.
†Fever AND either cough or sore throat.
‡Two or more of the following: fever, cough, runny nose, sore throat.
Page created: December 20, 2012
Page updated: December 20, 2012
Page reviewed: December 20, 2012
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