Volume 19, Number 1—January 2013
Letter
Cronobacter sakazakii ST4 Strains and Neonatal Meningitis, United States
Sumyya Hariri, Susan Joseph, and Stephen J. Forsythe
Table
Multilocus sequence typing of Cronobacter isolates received by the CDC during 2011*
| Cronobacter species | NTU strain ID no. | CDC patient ID no. | ST | Location | Isolation source | Comment |
|---|---|---|---|---|---|---|
| C. sakazakii | 1579 | 2012-05-05 | 4 | Missouri | CSF of <1 mo male, term infant; exposed to PIF | Patient died |
| 1566 | 2011-12-02 | 4 | Ohio | CSF of 1 mo male infant; exposed to PIF | From twin of patient 2011-12-03 | |
| 1567 | 2011-12-03 | 4 | Ohio | Feces of 1 mo male infant; exposed to PIF | From twin of patient 2011-12-02; asymptomatic | |
| 1568 | 2011-12-04 | 4 | Ohio | Opened PIF | Formula associated with 2011-12-02 and -03 | |
| 1570 | 2011-21-01 | 4 | Minnesota | CSF of <1 mo male, term infant; exposed to PIF | Brain infarction | |
| 1571 | 2011-21-03-01 | 4 | Minnesota | Opened PIF | Formula associated with 2011-21-01 | |
| 1576 | 2193-02 | 4 | Michigan | Tracheal secretion of <1 mo male, pre-term infant (30-wk EGA); not exposed to PIF | Symptoms were not caused by Cronobacter infection. Fortified breast milk fed only after culture was obtained | |
| 1565 | 2011-12-01 | 107 | Michigan | CSF of <1 mo male, term infant; exposed to PIF | Brain abscess; outcome unknown. Single locus variant of ST4 | |
| 1572 | 2011-21-03-02 | 108 | Minnesota | Opened PIF | Single locus variant of ST4 | |
| 1577 | 2193-03 | 110 | Illinois | CSF of 1 mo female, term infant; exposed to PIF | Triple locus variant of ST4 | |
| 1578 | 2193-08-01 | 111 | Illinois | PIF reconstitution water | Bottled water associated with 2193-03 case | |
| 1573 | 2011-18-05-02 | 8 | Ohio | Opened PIF | Formula associated with 2011-18-01 and 2011-18-07 | |
| 1574 | 2011-18-01 | 8 | Ohio | Feces of 4 mo female, term infant; exposed to PIF | Diarrheal symptoms | |
| 1575 |
2011-18-07 |
8 |
Ohio |
Feces of ≈5 mo female, term infant; exposed to PIF |
Ongoing diarrhea; same patient as 2011-18-01 |
|
| C. malonaticus | 1569 | 2193-01 | 112 | Wisconsin | Blood of <1 mo male pre-term infant (32 week EGA); exposed to PIF | Clinical meningitis; patient died |
*NTU, Nottingham Trent University; ID, identification; CDC, Centers for Disease Control and Prevention; ST, sequence type; CSF, cerebrospinal fluid; PIF, powdered infant formula; EGA, estimated gestational age.
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Page updated: December 20, 2012
Page reviewed: December 20, 2012
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