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Volume 19, Number 10—October 2013
Letter

Human Infection with Eurasian Avian-like Influenza A(H1N1) Virus, China

Da-Yan Wang1, Shun-Xiang Qi1, Xi-Yan Li, Jun-Feng Guo, Min-Ju Tan, Guang-Yue Han, Yan-Fang Liu, Yu Lan, Lei Yang, Wei-Juan Huang, Yan-Hui Cheng, Xiang Zhao, Tian Bai, Zhao Wang, He-Jiang Wei, Ning Xiao, and Yue-Long ShuComments to Author 
Author affiliations: National Insititute for Viral Disease Control and Prevention, China CDC. Beijing, People’s Republic of China (D.-Y. Wang, X.-Y. Li, J.-F. Guo, M.-J. Tan, Y. Lan, L. Yang, W.-J. Huang, Y.-H. Cheng, X. Zhao, T. Bai, Z. Wang, N. Xiao, H.-J. Wei, Y.-L. Shu); Hebei Center for Disease Control and Prevention, Hebei Province, People’s Republic of China (S.-X. Qi, G.-Y. Han, Y.-F. Liu)

Main Article

Table

Cross-reactive antibody response against avian-like influenza A(H1N1) virus in pediatric and adult recipients of seasonal trivalent inactivated influenza vaccines, China, 2013*†

Age
group, y Antigen Increase ≥4, %‡ Geometric mean titer

%Titer ≥40

%Titer ≥160
Before vac. After vac. Before vac. After vac. Before vac. After vac.
Children, n = 25 A/California/7/2009 60.0 21.1 121.3 44.0 84.0 16.0 60.0
3–5 HB/1250/12 24.0 12.8 25.7 28.0 56.0 0 24.0
Adults, n = 30 A/California/7/2009 70.0 14.8 156.3 26.7 76.7 0 60.0
18–59 HB/1250/12 6.7 8.1 31.7 6.7 56.7 0 23.3
Elderly adults, n = 30 A/California/7/2009 46.7 10.5 52.8 10.0 53.3 0 30.0
>60 HB/1250/12 26.7 5.7 11.5 0 26.7 0 6.7

*Vac., vaccination.
†All children received 2 doses of vaccine with an interval of 1 month. The composition of the trivalent vaccine were A/Christchurch/16/2010(NIB-74xp) (A/California/7/2009-like), A/Victoria/361/2011 (H3N2)IVR-165, and B/Hubei-Wujiagang/158/2009. Serum samples were obtained from vaccine recipients living in northern (children) and southern (adults and elderly adults) China.
‡Increase in antibody titer.

Main Article

1These authors contributed equally to this article.

Page created: September 17, 2013
Page updated: September 17, 2013
Page reviewed: September 17, 2013
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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