Volume 19, Number 10—October 2013
Letter
Human Infection with Eurasian Avian-like Influenza A(H1N1) Virus, China
Table
Cross-reactive antibody response against avian-like influenza A(H1N1) virus in pediatric and adult recipients of seasonal trivalent inactivated influenza vaccines, China, 2013*†
Age group, y | Antigen | Increase ≥4, %‡ | Geometric mean titer |
%Titer ≥40 |
%Titer ≥160 |
||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Before vac. | After vac. | Before vac. | After vac. | Before vac. | After vac. | ||||||
Children, n = 25 | A/California/7/2009 | 60.0 | 21.1 | 121.3 | 44.0 | 84.0 | 16.0 | 60.0 | |||
3–5 | HB/1250/12 | 24.0 | 12.8 | 25.7 | 28.0 | 56.0 | 0 | 24.0 | |||
Adults, n = 30 | A/California/7/2009 | 70.0 | 14.8 | 156.3 | 26.7 | 76.7 | 0 | 60.0 | |||
18–59 | HB/1250/12 | 6.7 | 8.1 | 31.7 | 6.7 | 56.7 | 0 | 23.3 | |||
Elderly adults, n = 30 | A/California/7/2009 | 46.7 | 10.5 | 52.8 | 10.0 | 53.3 | 0 | 30.0 | |||
>60 | HB/1250/12 | 26.7 | 5.7 | 11.5 | 0 | 26.7 | 0 | 6.7 |
*Vac., vaccination.
†All children received 2 doses of vaccine with an interval of 1 month. The composition of the trivalent vaccine were A/Christchurch/16/2010(NIB-74xp) (A/California/7/2009-like), A/Victoria/361/2011 (H3N2)IVR-165, and B/Hubei-Wujiagang/158/2009. Serum samples were obtained from vaccine recipients living in northern (children) and southern (adults and elderly adults) China.
‡Increase in antibody titer.
1These authors contributed equally to this article.