Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 19, Number 12—December 2013
Letter

Hepatitis E and Lymphocytic Leukemia in Man, Italy

Maria T. GiordaniComments to Author , Paolo Fabris, Enrico Brunetti, Sam Goblirsch, and Luisa Romanò
Author affiliations: San Bortolo Hospital, Vicenza, Italy (M.T. Giordani, P. Fabris); University of Pavia, Pavia, Italy (E. Brunetti); Winona Health, Winona, Minnesota, USA (S. Goblirsch); University of Milan, Milan, Italy (L. Romanò)

Main Article

Figure

Clinical and laboratory data for a 60-year-old man with hepatitis E and lymphocytic leukemia, Italy, 2012.  Start of ribavirin treatment and virologic response are indicated. A differential diagnosis was obtained by using abdominal ultrasound, which showed an enlarged hypoechogenic liver and thickening of the gallbladder wall (5 mm) with gallstones in the lumen, but a regular biliary tree. An enlarged spleen (bipolar diameter 15.07 cm) and lymph nodes were attributed to chronic lymphocytic leuke

Figure. . Clinical and laboratory data for a 60-year-old man with hepatitis E and lymphocytic leukemia, Italy, 2012. Start of ribavirin treatment and virologic response are indicated. A differential diagnosis was obtained by using abdominal ultrasound, which showed an enlarged hypoechogenic liver and thickening of the gallbladder wall (5 mm) with gallstones in the lumen, but a regular biliary tree. An enlarged spleen (bipolar diameter 15.07 cm) and lymph nodes were attributed to chronic lymphocytic leukemia. Test results for the following markers were negative: viral hepatitis A, B, and C; hepatitis B virus DNA (nested PCR; Roche, Switzerland); hepatitis C virus (nested PCR; Roche); cytomegalovirus virus DNA; Epstein-Barr virus; Q fever; agglutination for Leptospira spp. (Galton's test); enteric fever; Borrelia spp.; Bartonella spp.; autoantibodies (anti-nuclear, anti–liver kidney microsomal, anti-mitochondrial); blood and feces cultures; and ova and parasites in feces. HEV, hepatitis E virus; NA, not available; AST, aspartate aminotransferase; ALT, alanine aminotransferase. Reference ranges were 8–48 IU/L for AST, 7–55 IU/L for ALT, and 0.1–1.0 mg/dL for total bilirubin.

Main Article

Page created: November 20, 2013
Page updated: November 20, 2013
Page reviewed: November 20, 2013
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external