Volume 19, Number 3—March 2013
Dispatch
Prioritizing Tuberculosis Clusters by Genotype for Public Health Action, Washington, USA
Scott Lindquist
, Sheanne Allen, Kim Field, Smita Ghosh, Maryam B. Haddad, Masahiro Narita, and Eyal Oren
, Sheanne Allen, Kim Field, Smita Ghosh, Maryam B. Haddad, Masahiro Narita, and Eyal Oren
Table
Comparison of geospatial analysis results and expert panel priority status rankings for county-level genotype clusters of TB cases, Washington, USA, 2005–2010*
| County | Spoliogtype | 12-locus MIRU-VNTR | Period 1† |
Period 2† |
Key epidemiologic features‡ | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| No. cases | LLR | Expert priority | No. cases | LLR | Expert priority | |||||
| A | 000000000003771 | 223321153643 | 32 | 31.8 | High | 19 | 18.3 | High | H, SA | |
| 000000000003771 | 223325173533 | 17 | 0.1 | High | 8 | 0.4 | Low | FB | ||
| 677777477413771 | 254326223432 | 14 | 0.2 | Low | 14 | 0.1 | Low | FB | ||
| 703377400001771 | 227425113434 | 4 | 1.2 | Low | 6 | 2.9 | Low | FB, H | ||
| 000000000003771 | 223325153533 | 3 | 0.5 | Low | 1 | <0.01 | Low | FB | ||
| 000000000003771 | 223325163533 | 3 | 0.2 | Low | 7 | 1.7 | Low | FB, SA | ||
| 677777477413771 | 254326223422 | 6 | 1.3 | Low | 4 | 0.4 | Low | FB | ||
| 777000377760771 | 225125113322 | 3 | 0.6 | Low | 3 | 1.0 | Low | FB | ||
| 000000000003771 | 222325173543 | 9 | 2.4 | High | 3 | 0.1 | High | H, SA | ||
| 777777777760771 | 225125113322 | 3 | 0.7 | Low | 2 | 0.4 | Low | FB | ||
| 000000000003771 | 222325173533 | 7 | 2.6 | High | 8 | 2.3 | High | |||
| 000000000003771 | 223325173433 | 3 | 1.5 | Low | 1 | 0.2 | Low | FB | ||
| 000000000003771 | 223325133533 | 3 | 1.4 | Low | 0 | <0.01 | Low | FB | ||
| 000000000000000 | 223325123534 | 4 | 9.2 | High | 0 | <0.01 | Low | H, SA | ||
| 777776777620601 |
224325153323 |
3 |
4.4 |
High |
0 |
0.03 |
Low |
H, SA |
||
| B |
000000000003771 |
223425173563 |
13 |
19.5 |
High |
8 |
13 |
High |
H, SA |
|
| C | 677777477413771 | 254326223432 | 6 | 1.3 | Low | 3 | <0.01 | Low | FB, SA | |
| 777776777760771 |
125325153225 |
7 |
9.8 |
High |
2 |
1.8 |
High |
H, SA |
||
| D | 677777477413771 | 254326223432 | 5 | 0.8 | Low | 4 | 0.4 | Low | FB | |
| 777776757760771 |
223325143324 |
6 |
8.7 |
High |
1 |
1.2 |
Low |
|||
| E | 677777477413771 | 254326223432 | 3 | 1.0 | Low | 2 | 0.9 | Low | FB | |
*LLRs >5.0 (boldface) indicate greater possibility that the cluster represents geographically concentrated TB cases, a proxy for recent TB transmission). TB, tuberculosis; MIRU-VNTR, mycobacterial interspersed repetitive unit–variable number tandem repeat; LLR, log-likelihood ratio, a measure of geospatial concentration; H, homelessness; FB, foreign born; SA, substance abuse.
†Period 1, January 1, 2005–December 31, 2007; period 2, January 1, 2008–December 31, 2010.
‡Blank cells indicate none present.
Page created: February 01, 2013
Page updated: February 01, 2013
Page reviewed: February 01, 2013
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