Volume 19, Number 5—May 2013
Letter
Mycobacterium tuberculosis Complex in Remains of 18th–19th Century Slaves, Brazil
Lauren H. Jaeger, Sheila M.F.M. de Souza, Ondemar F. Dias, and Alena M. Iñiguez
Table
Results of genetic analyses of Mycobacterium tuberculosis complex hybridization and human mtDNA haplotypes from human bone samples collected from Pretos Novos Cemetery, Rio de Janeiro, Brazil*
| Sample | TB hybridization |
Nucleotide position of mtDNA hypervariable segment I† |
mtDNA haplotype | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IS6110 | IS1081 | 129 | 145 | 148 | 172 | 187 | 189 | 213 | 223 | 278 | 311 | 319 | 320 | |||
| CRS | NA | NA | G | G | C | T | C | C | G | C | C | T | G | C | H | |
| PN1 | + | + | ||||||||||||||
| PN2 | − | − | ||||||||||||||
| PN3 | − | − | ||||||||||||||
| PN4 | − | − | ||||||||||||||
| PN5 | − | − | ||||||||||||||
| PN6 | − | − | G | G | C | T | C | T | G | T | C | C | G | T | L3e2 | |
| PN7 | − | − | ||||||||||||||
| PN8 | + | + | ||||||||||||||
| PN9 | − | − | ||||||||||||||
| PN10 | − | − | ||||||||||||||
| PN11 | − | − | ||||||||||||||
| PN12 | − | − | ||||||||||||||
| PN13 | + | + | ||||||||||||||
| PN14 | − | − | G | G | C | T | C | T | G | T | C | T | A | C | L3d1 | |
| PN15 | + | − | A | A | C | T | T | C | A | T | L1c2 | |||||
| PN16 | − | − | ||||||||||||||
*The cemetery was used as a burial ground for African slaves who died in slave markets during 1769–1830. Blank cells mean target could not be retrieved. mtDNA, mitochondrial DNA; TB, tuberculosis; IS, insertion sequence; CRS, Cambridge Reference Sequence (accession no. AB055387); NA, not applicable; PN, bone samples from humans buried in Pretos Novos Cemetery; Abs, absence of nucleotide.
†The prefix 16 has been omitted from the nucleotide numbers.
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