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Volume 19, Number 5—May 2013

Research

World Health Organization International Standard to Harmonize Assays for Detection of Hepatitis E Virus RNA

Sally A. BaylisComments to Author , Johannes Blümel, Saeko Mizusawa, Keiji Matsubayashi, Hidekatsu Sakata, Yoshiaki Okada, C. Micha Nübling, Kay-Martin O. Hanschmann, and the HEV Collaborative Study Group
Author affiliations: Paul-Ehrlich-Institut, Langen, Germany (S.A. Baylis, J. Blümel, C.M. Nübling, K.-M.O. Hanschmann); National Institute of Infectious Diseases, Tokyo, Japan (S. Mizusawa, Y. Okada); Japanese Red Cross Hokkaido Block Blood Center, Sapporo, Japan (K. Matsubayashi, H. Sakata)

Main Article

Figure 1

Histograms showing results for quantitative and qualitative assays conducted by 23 laboratories for the determination of the hepatitis E virus (HEV) RNA content of sample 1 (A), sample 2 (B), sample 3 (C), and sample 4 (D). White indicates quantitative assays (log10 copies/mL); gray indicates qualitative assays (log10 nucleic acid amplification technique (NAT)–detectable units/mL). Number of laboratories is indicated on the vertical axis. Laboratory code numbers are indicated in the respective b

Figure 1. . . Histograms showing results for quantitative and qualitative assays conducted by 23 laboratories for the determination of the hepatitis E virus (HEV) RNA content of sample 1 (A), sample 2 (B), sample 3 (C), and sample 4 (D). White indicates quantitative assays (log10 copies/mL); gray indicates qualitative assays (log10 nucleic acid amplification technique (NAT)–detectable units/mL). Number of laboratories is indicated on the vertical axis. Laboratory code numbers are indicated in the respective boxes.

Main Article

1Members of the HEV Collaborative Study Group are listed at the end of this article.

2In memory of Thomas Laue.

Page created: April 01, 2013
Page updated: April 01, 2013
Page reviewed: April 01, 2013
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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