Volume 19, Number 5—May 2013
Research
World Health Organization International Standard to Harmonize Assays for Detection of Hepatitis E Virus RNA
Table 1
HEV strains diluted and lyophilized as candidate standards in study to establish a WHO International Standard for HEV RNA NAT-based assays*
Virus strain | HEV RNA, copies/mL | Genotype | GenBank accession no. | IgM/IgG against HEV | Alanine aminotransferase, IU/L |
---|---|---|---|---|---|
HRC-HE104 | 1.6 × 107 | 3a | AB630970 | −/− | 36 |
JRC-HE3 | 2.5 × 107 | 3b | AB630971 | +/− | 398 |
*Strains were provided by the Japanese Red Cross Society Blood Service Headquarters, Tokyo, Japan. HEV, hepatitis E virus; WHO, World Health Organization; NAT, nucleic acid amplification technique.
1Members of the HEV Collaborative Study Group are listed at the end of this article.
2In memory of Thomas Laue.