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Volume 19, Number 5—May 2013


Changes in Severity of Influenza A(H1N1)pdm09 Infection from Pandemic to First Postpandemic Season, Germany

Nicola Lehners1, Steffen Geis1, Christoph Eisenbach, Kai Neben, and Paul SchnitzlerComments to Author 
Author affiliations: Author affiliation: University of Heidelberg, Heidelberg, Germany

Main Article

Table 4

Demographic and clinical characteristics of patients infected with influenza A(H1N1)pdm09 who died, Germany, 2010–11*

Patient no. Age, y/sex Underlying condition Bacterial coinfection Pneumonia type (per chest radiograph) Complications (other than pneumonia) Antiviral therapy Mechanical ventilation Length of hospital stay, d
1 28/M Lliver/kidney transplant No Bipulmonary Renal and liver failure, SIRS Yes Yes 13
2 75/F CHD, COPD, post breast cancer No Unilobar Myocardial infarction Yes Yes 37
3 68/M Multiple myeloma No Bipulmonary Pneumothorax Yes Yes, + ECMO 56
4 71/M Multiple myeloma No Bipulmonary Yes Yes, + ECMO 19
5 18/F None No No Myocarditis No Yes 2
6 57/F Multiple myeloma Enterococcus faecium Bipulmonary RSV coinfection Yes Yes, + NO 12
7 52/F Multiple myeloma No Bipulmonary Yes Yes, + NO 17
8 85/F Parkinson disease, epilepsy No Bipulmonary Myocardial infarction No Yes, + NO 4
9 65/F Esophageal carcinoma No Bipulmonary ARDS Yes Yes, + NO, + ECMO 52
10 61/F PBC, chronic hepatitis B, diabetes, COPD Enterococcus cloacae, Achromobacter sp. Bipulmonary Renal and liver failure, sepsis, lung edema Yes Yes, + NO 53
11 45/F Acute leptospirosis E. faecium, Leptospira sp. Bipulmonary Renal and liver failure Yes Yes 13
12 49/M Colitis ulcerosa Escherichia coli Bipulmonary Perforation of colon, hemorrhagic shock, lung edema Yes Yes, + NO, + ECMO 8
13 61/F CHD, CKD Klebsiella pneumoniae Bipulmonary Septic shock Yes Yes, + NO 28
14 53/F Liver cirrhosis E. faecium Bipulmonary Renal and liver failure, septic shock, CMV reactivation, aspergillosis Yes Yes 43
15 52/M Multiple myeloma, post allogenic transplant E. faecium Bipulmonary GvHD 4, cerebral hemorrhage, CMV reactivation, progressive myeloma Yes Yes 46

*SIRS, systemic inflammatory response syndrome; CHD, congestive heart disease; COPD, chronic obstructive pulmonary disease; ECMO, extracorporeal membrane oxygenation; RSV, respiratory syncytial virus; NO, nitric oxide; ARDS, acute respiratory distress syndrome; PBC, primary biliary cirrhosis; CKD, chronic kidney disease; CMV, cytomegalovirus; GvHD, graft versus host disease.

Main Article

1These authors contributed equally to this article.