Volume 19, Number 5—May 2013
Research
Changes in Severity of Influenza A(H1N1)pdm09 Infection from Pandemic to First Postpandemic Season, Germany
Table 2
Demographic and clinical characteristics of influenza- infected patients stratified by severity, University Hospital Heidelberg, 2009–10 and 2010–11, Germany*
| Characteristic | No. (%) patients |
p value | |
|---|---|---|---|
| Nonsevere diseases | Severe disease | ||
| Total no. admitted patients | 128 | 50 | |
| Male sex | 61 (48) | 31 (62) | 0.08 |
| Age, y, mean | 18.4 | 47.9 | <0.05 |
| Days in hospital | 6.4 | 20.2 | <0.05 |
| Pregnant | 8 (6) | 1 (2) | 0.45 |
| Pneumonia | 22 (17) | 40 (80) | <0.05 |
| Underlying medical condition | 64 (50) | 45 (90) | <0.05 |
| Immunosuppression | 35 (27) | 28 (56) | <0.05 |
| Cancer | 1 (1) | 5 (10) | <0.05 |
| Blood malignancy | 12 (9) | 13 (26) | <0.05 |
| Solid organ transplant | 16 (13) | 5 (10) | 0.64 |
| Autoimmune | 6 (5) | 5 (10) | 0.19 |
| Other | 2 (2) | 3 (6) | 0.11 |
| Chronic lung disease | 11 (9) | 11 (22) | <0.05 |
| Cardio vascular disease | 29 (23) | 29 (58) | <0.05 |
| Renal impairment | 14 (11) | 15 (30) | <0.05 |
| Diabetes | 5 (4) | 12 (24) | <0.05 |
| Metabolic dysfunction | 16 (13) | 12 (24) | 0.06 |
| Neurologic impairment | 16 (13) | 7 (14) | 0.79 |
| CRP level on admission, mg/L† | 34.6 (range 1.99–213.6) | 86.7 (range 1.99–381.4) | <0.05 |
| Leukocyte count on admission, /nL† | 9.4 (range 1.9–108.7) | 10.1 (range 0.1–48.8) | 0.71 |
*CRP, C-reactive protein.
†Or the following day if not tested on admission.
1These authors contributed equally to this article.
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