Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 19, Number 6—June 2013
Letter

Vibrio cholerae O1 Isolate with Novel Genetic Background, Thailand–Myanmar

Kazuhisa OkadaComments to Author , Amonrattana Roobthaisong, Witaya Swaddiwudhipong, Shigeyuki Hamada, and Siriporn Chantaroj
Author affiliations: Thailand-Japan Research Collaboration Center on Emerging and Re-emerging Infections, Nonthaburi, Thailand (K. Okada, A. Roobthaisong, S. Hamada); Osaka University, Osaka, Japan (K. Okada, S. Hamada); Mae Sot General Hospital, Tak, Thailand (W. Swaddiwudhipong); and National Institute of Health, Nonthaburi (S. Chantaroj)

Main Article

Figure

Relationships among MS6, Vibrio cholerae O1 strain, isolated in Thailand in 2008, and other V. cholerae O1 strains based on 15 housekeeping genes referenced in Salim et al. (10). Boldface indicates the MS6 strain. The mutational (m) and recombinational (r) changes with gene names are marked on the branches (r ≠ r2). Numbers in parentheses represent the year of isolation. DNA gyrase subunit B gene (gyrB) of MS6 is 22 nt differences from that of the seventh pandemic clone. Two genes of MS6, malP a

Figure. . . Relationships among MS6, Vibrio cholerae O1 strain, isolated in Thailand in 2008, and other V. cholerae O1 strains based on 15 housekeeping genes referenced in Salim et al. (10). Boldface indicates the MS6 strain. The mutational (m) and recombinational (r) changes with gene names are marked on the branches (r ≠ r2). Numbers in parentheses represent the year of isolation. DNA gyrase subunit B gene (gyrB) of MS6 is 22 nt differences from that of the seventh pandemic clone. Two genes of MS6, malP and pepN, exhibit novel sequence types based on results of a BLAST search (http://blast.ncbi.nlm.nih.gov/Blast.cgi).

Main Article

References
  1. Sack  DA, Sack  RB, Nair  GB, Siddique  AK. Cholera. Lancet. 2004;363:223–33. DOIPubMedGoogle Scholar
  2. Okada  K, Roobthaisong  A, Nakagawa  I, Hamada  S, Chantaroj  S. Genotypic and PFGE/MLVA analyses of Vibrio cholerae O1: geographical spread and temporal changes of isolates during the 2007–2010 cholera outbreaks in Thailand. PLoS ONE. 2012;7:e30863. DOIPubMedGoogle Scholar
  3. Safa  A, Nair  GB, Kong  RYC. Evolution of new variants of Vibrio cholerae O1. Trends Microbiol. 2010;18:46–54. DOIPubMedGoogle Scholar
  4. Dziejman  M, Balon  E, Boyd  D, Fraser  CM, Heidelberg  JF, Mekalanos  JJ. Comparative genomic analysis of Vibrio cholerae: genes that correlate with cholera endemic and pandemic disease. Proc Natl Acad Sci U S A. 2002;99:1556–61. DOIPubMedGoogle Scholar
  5. Chun  J, Grim  CJ, Hasan  NA, Lee  JH, Choi  SY, Haley  BJ, Comparative genomics reveals mechanism for short-term and long-term clonal transitions in pandemic Vibrio cholerae. Proc Natl Acad Sci U S A. 2009;106:15442–7. DOIPubMedGoogle Scholar
  6. Taviani  E, Grim  CJ, Choi  J, Chun  J, Haley  B, Hasan  NA, Discovery of novel Vibrio cholerae VSP-II genomic islands using comparative genomic analysis. FEMS Microbiol Lett. 2010;308:130–7.PubMedGoogle Scholar
  7. Grim  CJ, Choi  J, Chun  J, Jeon  YS, Taviani  E, Hasan  NA, Occurrence of the Vibrio cholerae seventh pandemic VSP-I island and a new variant. OMICS. 2010;14:1–7. DOIPubMedGoogle Scholar
  8. O’Shea  YA, Reen  FJ, Quirke  AM, Boyd  EF. Evolutionary genetic analysis of the emergence of epidemic Vibrio cholerae isolates on the basis of comparative nucleotide sequence analysis and Multilocus Virulence Gene Profiles. J Clin Microbiol. 2004;42:4657–71 . DOIPubMedGoogle Scholar
  9. Talkington  D, Bopp  C, Tarr  C, Parsons  MB, Dahourou  G, Freeman  M, Characterization of toxigenic Vibrio cholerae from Haiti, 2010–2011. Emerg Infect Dis. 2011;17:2122–9.PubMedGoogle Scholar
  10. Salim  A, Lan  R, Reeves  PR. Vibrio cholerae pathogenic clones. Emerg Infect Dis. 2005;11:1758–60 . DOIPubMedGoogle Scholar

Main Article

Page created: May 06, 2013
Page updated: May 06, 2013
Page reviewed: May 06, 2013
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external