Volume 19, Number 6—June 2013
Synopsis
Zoonotic Mycobacterium bovis–induced Tuberculosis in Humans
Table 2
Overview of selected reports from Africa on zoonotic Mycobacterium bovis–induced TB in humans*
ID | Country | Setting | Sampling | Detection | Years | M. bovis† | TB‡ | %§ | 95% CI | Location |
---|---|---|---|---|---|---|---|---|---|---|
1131 | Tanzania | NA | Conv. | Mol. | NA | 20 | 53 | 37.7 | 24.8–52.1 | EPTB |
1131 | Tanzania | Arusha region | Conv. | Mol. | 1994 | 4 | 11 | 36.4 | 10.9–69.2 | EPTB |
1074 | Ethiopia | Butajira health center, southeastern Ethiopia | System. | Mol. | 2000/2001 | 11 | 35 | 31.4 | 16.9–49.3 | EPTB |
1074 | Ethiopia | NA | Conv. | Biochem. | NA | 14 | 48 | 29.2 | 17.0–44.1 | PTB |
15 | Ethiopia | Felegehiwot hospital | Conv. | Biochem. | 2007/2008 | 8 | 47 | 17.0 | 7.6–30.8 | Both |
65 | Ethiopia | NA | Conv. | Biochem. | NA | 7 | 42 | 16.7 | 7.0–31.4 | Both |
1074 | Ethiopia | Fitche Hospital TB clinic | Conv. | Biochem. | 2004/2005 | 7 | 42 | 16.7 | 7.0–31.4 | Both |
294 | Tanzania | Arusha region and Southern Highlands | Surv. | Biochem. | 1993–1996 | 7 | 44 | 15.9 | 6.6–30.1 | Both |
73 | Nigeria | Jos | Conv. | Biochem. | NA | 10 | 65 | 15.4 | 7.6–26.5 | PTB |
68 | Uganda | Karamojo region | Conv. | Mol. | NA | 3 | 24 | 12.5 | 2.7–32.4 | EPTB |
159 | Tanzania | Three districts in Arusha region | Surv. | Biochem. | 1999–2001 | 7 | 65 | 10.8 | 4.4–20.9 | EPTB |
459 | Malawi | Blantyre, Queen Elizabeth Central Hospital | Conv. | Biochem. | NA | 1 | 30 | 3.3 | 0.1–17.2 | PTB |
62 | Ghana | Korle-Bu Teaching Hospital | Conv. | Biochem. | 2003 | 2 | 64 | 3.1 | 0.4–10.8 | PTB |
464 | Madagascar | Institut d'Hygiène Sociale, Antananarivo | Conv. | Mol. | 1994 | 3 | 126 | 2.4 | 0.5–6.8 | PTB |
340 | Madagascar | Antananarivo | Surv. | Other | 1994/1995 | 2 | 156 | 1.3 | 0.2–4.6 | EPTB |
292 | Madagascar | Antananarivo, Antsirabe, Fianarantsoa, and Mahajanga | Rand. | Mol. | 1994/1995 | 4 | 316 | 1.3 | 0.3–3.2 | PTB |
243 | Uganda | Kampala | Conv. | Biochem. | 1995–1997 | 1 | 234 | 0.4 | 0.0–2.4 | PTB |
52 | Uganda | Kampala, Rubaga division | Surv. | Mol. | 2006 | 1 | 386 | 0.3 | 0.0–1.4 | PTB |
222 | Cameroon | Ouest Province | Surv. | Mol. | 1997/1998 | 1 | 455 | 0.2 | 0.0–1.2 | PTB |
80 | Burkina Faso | Health centers in Ouagadougou and Bobo Dioulasso | Conv. | Mol. | 2001 | 0 | 120 | 0.0 | 0.0–3.0¶ | PTB |
12 | Burundi | Bujumbara, Bubanza Hospital | Conv. | Mol. | 1987–1994 | 0 | 117 | 0.0 | 0.0–3.1¶ | Both |
165 | Chad | Chari-Baguirmi | Conv. | Mol. | 2002 | 0 | 10 | 0.0 | 0.0–30.8¶ | Both |
12 | Côte d'Ivoire | TB and rural health centers in Côte d’Ivoire | Cluster | Mol. | 1994–1996 | 0 | 320 | 0.0 | 0.0–1.1¶ | PTB |
464 | Madagascar | Antananarivo prison | Conv. | Mol. | 1994 | 0 | 36 | 0.0 | 0.0–9.7¶ | PTB |
12 | Sierra Leone | Western Area and Kenema districts | Surv. | Mol. | 2003/2004 | 0 | 97 | 0.0 | 0.0–3.7¶ | PTB |
32 | Uganda | Mbarara district | Rand. | Mol. | 2004/2005 | 0 | 70 | 0.0 | 0.0–5.1¶ | Both |
*TB, tuberculosis; ID, record identification number (Technical Appendix 2); NA, not available; Conv., convenience sample/not specified; Mol., molecular-based detection method; EPTB, extrapulmonary TB; System, systematic sampling; Biochem, biochemical detection method; PTB, pulmonary TB; Surv.,surveillance data; Rand., random sampling; Cluster, cluster sampling.
†Number of putative zoonotic cases of Mycobacterium bovis.
‡Total number of bacteriologically confirmed and characterized TB cases.
§%, proportion of zoonotic TB among all TB cases.
¶One-sided 97.5% CIs are indicated.