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Volume 19, Number 7—July 2013
Letter

Tick-borne Encephalitis Virus, Zealand, Denmark, 2011

Anders FomsgaardComments to Author , Mette E. Fertner, Sandra Essbauer, Alex Y. Nielsen, Stefan Frey, Pontus Lindblom, Per-Eric Lindgren, Rene Bødker, Manfred Weidmann, and Gerhard Dobler
Author affiliations: University of Southern Denmark, Odense, Denmark (A. Fomsgaard); Statens Serum Institut, Copenhagen, Denmark (A. Fomsgaard, M.E. Fertner, A.Y. Nielsen); Institut für Mikrobiologie der Bundeswehr, Munich, Germany (S. Essbauer, S. Frey, G. Dobler); Linköping University, Linköping, Sweden (P. Lindblom, P.-E. Lindgren); Technical University of Denmark, Copenhagen (R. Bødker); Abteilung Virologie, Universitätsmedizin Göttingen, Göttingen, Germany (M. Weidmann)

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Figure

A) Tick collection areas in Denmark. Red indicates ticks sampled from animals; blue indicates flagging. B) Neighbor-joining phylogenetic analysis of a 1,488-nt set of 78 tick-borne encephalitis virus (TBEV)–Eur E gene sequences including reference strains Neudoerfl (Austria) and Hypr 71 (South Moravia) performed in ClustalW with a 1,000 bootstrap approach (LASERGENE, MEGALIGN, DENDROSCOPE) outgrouped to Louping ill virus (data not shown). Sequence designations of central European strains as in (

Figure. . . A) Tick collection areas in Denmark. Red indicates ticks sampled from animals; blue indicates flagging. B) Neighbor-joining phylogenetic analysis of a 1,488-nt set of 78 tick-borne encephalitis virus (TBEV)–Eur E gene sequences including reference strains Neudoerfl (Austria) and Hypr 71 (South Moravia) performed in ClustalW with a 1,000 bootstrap approach (LASERGENE, MEGALIGN, DENDROSCOPE) outgrouped to Louping ill virus (data not shown). Sequence designations of central European strains as in (8). Dark gray indicates Denmark Bornholm clade; light gray indicates Swedish-Norwegian clade. For simplicity, some subtrees were collapsed; these are designated with region and number of sequences in the collapsed subtree in brackets.

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References
  1. Jääskeläinen  AE, Tonteri  E, Sironen  T, Pakarinen  L, Vaheri  A, Vapalahti  O. European subtype tick-borne encephalitis virus in Ixodes persulcatus ticks. Emerg Infect Dis. 2011;17:3235 . DOIPubMed
  2. Skarphédinsson  S, Jensen  PM, Kristiansen  K. Survey of tick-borne infections in Denmark. Emerg Infect Dis. 2005;11:105561 . DOIPubMed
  3. Randolph  SE, Rogers  DJ. Fragile transmission cycles of tick-borne encephalitis virus may be disrupted by predicted climate change. Proc Biol Sci. 2000;267:17414 . DOIPubMed
  4. Fomsgaard  A, Christiansen  CB, Bødker  R. First identification of tick-borne encephalitis in Denmark outside of Bornholm, August 2009. Euro Surveill. 2009;14:pii19326 .PubMed
  5. Schwaiger  M, Cassinotti  P. Development of a quantitative real-time RT-PCR assay with internal control for the laboratory detection of tick borne encephalitis virus (TBEV) RNA. J Clin Virol. 2003;27:13645 . DOIPubMed
  6. Fertner  ME, Mølbak  L, Boye Pihl  TP, Fomsgaard  A, Bødker  R. First detection of tick borne “Candidatus Neoehrlichia mikurensis” in Denmark 2011. Euro Surveill. 2012;17:pii20096 .PubMed
  7. Sonenshine  DE. Biology of ticks. Vol. 2. New York: Oxford University Press; 1993.
  8. Weidmann  M, Ruzek  D, Krivanec  K, Zöller  G, Essbauer  S, Pfeffer  M, Relation of genetic phylogeny and geographical distance of tick-borne encephalitis virus in central Europe. J Gen Virol. 2011;92:190616 . DOIPubMed
  9. Melik  W, Nilsson  AS, Johansson  M. Detection strategies of tick-borne encephalitis in Swedish Ixodes ricinus reveal evolutionary characteristics of emerging tick-borne flavivirus. Arch Virol. 2007;152:102734 . DOIPubMed
  10. Jaenson  TGT, Hjertqvist  M, Bergström  T, Lundkvist  A. Why is tick-borne encephalitis increasing? A review of the key factors causing the increasing incidence of human TBE in Sweden. Parasit Vectors. 2012;5:184.

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