Volume 19, Number 8—August 2013
Research
Accuracy of Diagnostic Methods and Surveillance Sensitivity for Human Enterovirus, South Korea, 1999–2011
Ji-Yeon Hyeon, Seoyeon Hwang, Hyejin Kim, Jaehyoung Song, Jeongbae Ahn, Byunghak Kang, Kisoon Kim, Wooyoung Choi, Jae Keun Chung, Cheon-Hyun Kim, Kyungsoon Cho, Youngmee Jee, Jonghyun Kim, Kisang Kim, Sun-Hee Kim, Min-Ji Kim, and Doo-Sung Cheon
Table 3
Five most frequent human enterovirus genotype rankings during the epidemic seasons in South Korea, by year, 1999–2011*
| Year | Genotype, no. (%) |
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|---|---|---|---|---|---|
| Rank 1 | Rank 2 | Rank 3 | Rank 4 | Rank 5 | |
| Phase 1† |
|||||
| 1999, n = 85 | CB2, 21 (24.7) | E6, 15 (17.7) | CB3, 10 (11.7) | E11, 8 (9.4) | E30, (8 (9.4) |
| 2000, n = 30 | EV71, 12 (40) | Polio Sabin strain, 9 (30) | CB2, 2 (2.7) | E6, 2 (2.7) | E11, 2 (2.7) |
| 2001, n = 26 | CB5, 12 (46.2) | CB3, 4 (15.4) | Polio Sabin strain, 3 (11.6) | CB2, 3 (11.6) | CB1, 3 (11.6) |
| 2002, n = 272 | E13, 70 (25.7) | E9, 59 (21.7) | E6, 53 (19.5) | E7, 24 (8.8) | CB3, 17 (6.3) |
| 2003, n = 54 | CB4, 16 (19.5) | E6, 10 (12.2) | E30, 7 (8.5) | CB1, 7 (8.5) | Polio Sabin strain, 5 (6.1) |
| 2004, n = 29 | Polio Sabin strain, 7 (24.1) | E30, 6 (20.7) | CB2, 5 (17.3) | CB1, 4 (13.8) | E6, 3 (10.3) |
| Phase 2‡ | |||||
| 2005, n = 369 | CB5, 159 (43.1) | E18, 127 (34.4) | CB3, 47 (12.7) | E9, 25 (6.8) | CB1, 7 (1.9) |
| 2006, n = 238 | E25, 56 (23.5) | E30, 48 (20.2) | E5, 28 (11.8) | CA16, 20 (8.4) | CB4, 18 (7.6) |
| 2007, n = 180 | CB2, 62 (34.4) | CA9, 28 (15.6) | EV71, 21 (11.7) | E16, 14 (7.8) | CA10, 10 (5.6) |
| Phase 3§ | |||||
| 2008, n = 626 | E30, 299 (47.8) | E6, 170 (27.2) | CA10, 33 (5.3) | CB3, 29 (4.6) | CB1, 27 (4.5) |
| 2009, n = 288 | EV71, 127 (44.1) | CB1, 70 (24.3) | CA2, 23 (8.0) | CA5, 20 (6.9) | CA14, 17 (5.9) |
| 2010, n = 402 | EV71, 190 (47.3) | CA6, 65 (16.2) | CB5, 32 (8.0) | CA9, 28 (7.0) | CA10, 19 (4.7) |
| 2011, n = 529 | EV71, 118 (22.3) | CA16, 109 (20.6) | CB5, 72 (13.6) | CB2, 70 (13.2) | E18, 42 (7.9) |
| Total, 1999–2011, n = 3,128 | EV71, 476 (14.9) | E30, 390 (12.5) | CB5, 290 (9.3) | E6, 261 (8.4) | CB2, 186 (6.0) |
*CB, coxsackievirus B; E, echovirus; EV, enterovirus; CA, coxsackievirus A.
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