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Volume 19, Number 9—September 2013
Dispatch

West Nile Virus RNA in Tissues from Donor Associated with Transmission to Organ Transplant Recipients

Dianna M. BlauComments to Author , Ingrid B. Rabe, Julu Bhatnagar, Rachel Civen, Kavita K. Trivedi, Dominique Rollin, Susan N. Hocevar, Matthew Kuehnert, J. Erin Staples, Sherif R. Zaki, Marc Fischer, and the West Nile Virus Transplant-Associated Transmission Investigation Team
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (D.M. Blau, J. Bhatnagar, D. Rollin, S.N. Hocevar, M. Kuehnert, S.R. Zaki); Centers for Disease Control and Prevention, Fort Collins, Colorado, USA (I.B. Rabe, J.E. Staples, M. Fischer); Los Angeles County Department of Public Health, Los Angeles, California, USA (R. Civen); California Department of Public Health, Richmond, California, USA (K. Trivedi)

Main Article

Table

WNV in tissues from solid organ donor associated with WNV transmission to solid organ transplant recipients*

Specimens tested Tests performed†
RT-PCR Cell culture IHC staining
Spleen/lymph node homogenate
 +
 +
 NT
Tissues
Skin + – –
Fat, tibia + – –
Tendon
Gracilis + – NT
Achilles – NT NT
Semitendinosus – NT NT
Tibialis – NT NT
Muscle
Attached to tibia + – –
Adjacent to gracilis tendon – – NT
Bone marrow
Femur + – –
Pelvis
 –
 NT
 NT
Bone, pelvic cortical ‡ NT NT
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Main Article

1Members of the West Nile Virus Transplant-Associated Transmission Investigation Team: Holenarasipur R. Vikram, David Mulligan, (Mayo Clinic, Phoenix); Gundeep Dhillon (Stanford University School of Medicine); Drew J. Winston, Johnny C. Hong (University of California Los Angeles Medical Center); Thomas Mone (OneLegacy); Marek J. Nowicki (Mendez National Institute of Transplantation); Joel Osborne, Pamela Rawlins (Musculoskeletal Transplant Foundation); and Selam A. Tecle (Arizona Department of Health Services).

Page created: August 20, 2013
Page updated: August 20, 2013
Page reviewed: August 20, 2013
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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