Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 2, Number 2—April 1996

Improved Serodiagnostic Testing for Lyme Disease: Results of a Multicenter Serologic Evaluation

Robert B. Craven*, Thomas J. Quan*, Raymond E. Bailey*, Raymond Dattwyler†, Raymond W. Ryan‡, Leonard H. Sigal§, Allen C. Steere¶, Bradley Sullivan#, Barbara J.B. Johnson*, David T. Dennis*, and Duane J. Gubler*
Author affiliations: *Centers for Disease Control and Prevention, Fort Collins, Colorado, USA; †State University of New York at Stony Brook, Stony Brook, New York, USA; ‡University of Connecticut Health Center, Farmington, Connecticut, USA; §University of Medicine and Dentistry of New Jersey–Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA; ¶Tufts/New England Medical Center, Boston, Massachusetts, USA; #Marshfield Clinic, Marshfield, Wisconsin, USA

Main Article

Table 1

Accuracy and precision of serologic tests for Lyme disease performed in 1992

Accuracy (%) Precision(%)
Investigator Sensitivity Specificity Case
patients Non-case-
patients WCS
CDC (WCS) 93 71 93 77 69
CDC (FLA) 92 82 92 79 62
1 73 99.5 89 99 98
2 76 99 82 99 97
3 79 98 91 97 94
4 49 91 79 94 93
5 40 72 63 74 77

ª Specimens from patients with suspected cases that had borderline (equivocal) seroreactivity in an enzyme-linked immunosorbent assay with whole-cell sonicate antigen (WCS).

Main Article

Page created: December 20, 2010
Page updated: December 20, 2010
Page reviewed: December 20, 2010
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.