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Volume 2, Number 2—April 1996

Transfusion-Associated Malaria

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To the Editor: A recent article by Zucker (1) described two cases of malaria that were probably transfusion associated. A case of transfusion-associated malaria in which the source was identified was reported in San Francisco in 1991. The case was in an elderly man in whom malaria infection developed after coronary bypass surgery.

The patient was born in China and immigrated to the United States in 1940. His only travel outside the United States was a trip to Hong Kong in 1951 for 6 months. The patient’s wife was born in China and had malaria in 1941 during World War II. She received no treatment at that time or at any other time. She came to the United States in 1960 and has not left the country since.

The patient had six donors, five of whom had no history of malaria, and had negative serologic test results for all four malaria species. Both the patient and his wife had blood smears positive for P. malariae. The patient’s wife had positive serologic test results for P. vivax and P. ovale (1:64), for P. falciparum (1:258), and for P. malariae (1:1024).


Frances Taylor

Author affiliation: Bureau of Epidemiology ,Disease Control, and AIDS, San Francisco, California, USA



  1. Zucker  J. Changing patterns of autochthonous malaria transmission in the United States: A review of current outbreaks. Emerg Infect Dis. 1996;2:3743. DOIPubMed


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DOI: 10.3201/eid0202.960216

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Table of Contents – Volume 2, Number 2—April 1996

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