Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 2, Number 4—October 1996
Dispatch

Encephalitis Caused by a Lyssavirus in Fruit Bats in Australia

Graeme C. Fraser*, Peter T. Hooper†, Ross A. Lunt†, Allan R. Gould†, Laurence J. Gleeson†, Alex D. Hyatt†, Gail M. Russell†, and Jaqueline A. Kattenbelt†
Author affiliations: *NSW Department of Agriculture, Wollongbar, Australia; †CSIRO Division of Animal Health, Geelong, Australia

Main Article

Table 1

Amino acid sequences of the virus designated pteropid lyssavirus (PLV) and those of rabies and rabies-like virusesa,b

PLVc PV 4FRA POL 8FRA AS FIN HOL NGA Genotype
PLV -
PV 92 - 1
4FRA 93 99 - 1
POL 93 94 94 - 5
8FRA 93 94 94 100 - 5
AS 89 90 91 95 95 - 4
FIN 85 87 88 87 87 84 - 6
HOL 85 88 89 87 87 83 98 - 6
NGA 82 82 83 85 85 85 76 77 - 2
MOK 76 75 76 79 79 80 72 71 86 3

a Described in Ref. 13.
b Comparisons were made of cognate regions of the N protein (amino acids 298 to 426 inclusive). Genebank accession numbers are given in brackets. PV, PV rabies virus (X03673); 4FRA, fox rabies virus (U22844); POL, European bat virus (U22844, 8615POL, EBV1); 8FRA, European bat virus (U22845, 8918FRA, EBV1); AS, Duvenhage virus (U22848); FIN, European bat virus (U22846, 9007FIN, EBV2); HOL, European bat virus (U22847, 9018HOL, EBV2); NGA, Lagos bat virus (U22842), Mokola virus (U22843).
c PLV, the virus now reported, provisionally designated pteropid lyssavirus; PV, PV rabies virus (X03673); 4FRA, fox rabies virus (U22844); POL, European bat virus (U22844, 8615POL, ELB1); 8FRA, European bat virus (U22845, 8918FRA, EBV1); AS, Duvenhage virus (U22848); Fin, European bat virus (U22846, 9007FIN, EBV2); HOL, European bat virus (U22847, 9018HOL, EBV2); NGA, Lagos bat virus (U22842), Mokola virus (U22843).

Main Article

References
  1. Bourhy  H, Kissi  B, Lafon  M, Sacramento  D, Tordo  N. Antigenic and molecular characterisation of bat rabies virus in Europe. J Clin Microbiol. 1992;30:241926.PubMed
  2. Calisher  CH, Karabatsos  N, Zeller  H, Digoutte  J-P, Tesh  RB, Shope  RE, Antigenic relationship among rhabdoviruses from vertebrates and hematophagous arthropods. Intervirology. 1989;30:24157.PubMed
  3. Brass  DA. Rabies in bats: Natural history and public health implications. Ridgerfield, Connecticut: Livia Press, 1994.
  4. Geering  WA, Forman  AJ, Nunn  MJ. Exotic diseases of animals: a field guide for veterinarians. Canberra: Australian Government Printing Service, 1995.
  5. McColl  KA, Gould  AR, Selleck  PW, Hooper  PT, Westbury  HA, Smith  JS. Polymerase chain reaction and other laboratory techniques in the diagnosis of long incubation rabies in Australia. Aust Vet J. 1993;70:849. DOIPubMed
  6. Webb  NJ, Tidemann  CR. Mobility of Australian flying-foxes, Pteropus spp. (Megachiroptera): evidence from genetic variation. Proc R Soc Lond Biol Sci. 1996;263:497502. DOI
  7. Ride  WDL. A guide to the native mammals of Australia. Melbourne: Oxford University Press, 1970.
  8. Richards  GC, Hall  LS. Placental Mammals, Bats, Order: Chiroptera. In: Strahan R, editor. The Australian museum complete book of Australian mammals. Sydney: Angus and Robertson, 1983.
  9. Young  PL, Halpin  K, Selleck  PW, Field  H, Gravel  JL, Kelly  MA, Serologic evidence for the presence in pteropus bats of a paramyxovirus related to equine morbillivirus. Emerg Infect Dis. 1996;2:23940. DOIPubMed
  10. Feiden  W, Kaiser  E, Gerhard  L, Dahme  E, Gylstorff  B, Wandeler  A, Immunohistochemical staining of rabies virus antigen with monoclonal and polyclonal antibodies in paraffin tissue sections. Zentralbl Veterinarmed [C]. 1988;35:24755.
  11. Smith  JS, Yager  PA, Baer  GM. A rapid tissue culture test for determining rabies neutralising antibody. In: Kaplan MM and Koprowski H, editors. Laboratory Techniques in Rabies, 3rd ed. Geneva, Switzerland: World Health Organization, 1973.
  12. Bouhry  H, Kissi  B, Tordo  N. Molecular diversity of the Lyssavirus genus. Virology. 1993;194:7081. DOIPubMed
  13. Kissi  B, Tordo  M, Bourhy  H. Genetic polymorphism in the rabies virus nucleoprotein gene. Virology. 1995;209:52637. DOIPubMed
  14. Wiktor  TJ, Koprowski  H. Antigenic variants of rabies virus. J Exp Med 1980;152:99-111.15
  15. Smith  JS. Rabies virus epitopic variation: use in ecologic studies. Adv Virus Res. 1989;36:21553. DOIPubMed
  16. Fekadu  M, Shaddock  JH, Sanderlin  DW, Smith  JS. Efficacy of rabies vaccines against Duvenhage virus isolated from European house bats (Eptesicus serotinus), classic rabies and rabies-related viruses. Vaccine. 1988;6:5339. DOIPubMed

Main Article

Page created: December 21, 2010
Page updated: December 21, 2010
Page reviewed: December 21, 2010
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external