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Volume 2, Number 4—October 1996

Encephalitis Caused by a Lyssavirus in Fruit Bats in Australia

Graeme C. Fraser*, Peter T. Hooper†, Ross A. Lunt†, Allan R. Gould†, Laurence J. Gleeson†, Alex D. Hyatt†, Gail M. Russell†, and Jaqueline A. Kattenbelt†
Author affiliations: *NSW Department of Agriculture, Wollongbar, Australia; †CSIRO Division of Animal Health, Geelong, Australia

Main Article

Table 2

Reactivity patterns of nucleocapsid monoclonal antibodies (Mab) with rabies (CVS-11) and pteropid lyssavirus (PLV)

MAbb Specificitya CVS-11 PLV
W502-2c lyssavirus + +
HAMd lyssavirus + +
C15-2e rabies + -
62-143-1f rabies + +
62-3-1f rabies +, EBV + + -
62-146-3f rabies +, DUVV - + +
W422c Mokola +, LBV + - -

a + indicates a positive reaction; - indicates a negative reaction
b Monoclonal antibody were specificities indicated by the following sources:
c (14,15); d (10); e (J Smith, pers. comm.); f (15,16)

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  1. Bourhy  H, Kissi  B, Lafon  M, Sacramento  D, Tordo  N. Antigenic and molecular characterisation of bat rabies virus in Europe. J Clin Microbiol. 1992;30:241926.PubMedGoogle Scholar
  2. Calisher  CH, Karabatsos  N, Zeller  H, Digoutte  J-P, Tesh  RB, Shope  RE, Antigenic relationship among rhabdoviruses from vertebrates and hematophagous arthropods. Intervirology. 1989;30:24157.PubMedGoogle Scholar
  3. Brass  DA. Rabies in bats: Natural history and public health implications. Ridgerfield, Connecticut: Livia Press, 1994.
  4. Geering  WA, Forman  AJ, Nunn  MJ. Exotic diseases of animals: a field guide for veterinarians. Canberra: Australian Government Printing Service, 1995.
  5. McColl  KA, Gould  AR, Selleck  PW, Hooper  PT, Westbury  HA, Smith  JS. Polymerase chain reaction and other laboratory techniques in the diagnosis of long incubation rabies in Australia. Aust Vet J. 1993;70:849. DOIPubMedGoogle Scholar
  6. Webb  NJ, Tidemann  CR. Mobility of Australian flying-foxes, Pteropus spp. (Megachiroptera): evidence from genetic variation. Proc R Soc Lond Biol Sci. 1996;263:497502. DOIGoogle Scholar
  7. Ride  WDL. A guide to the native mammals of Australia. Melbourne: Oxford University Press, 1970.
  8. Richards  GC, Hall  LS. Placental Mammals, Bats, Order: Chiroptera. In: Strahan R, editor. The Australian museum complete book of Australian mammals. Sydney: Angus and Robertson, 1983.
  9. Young  PL, Halpin  K, Selleck  PW, Field  H, Gravel  JL, Kelly  MA, Serologic evidence for the presence in pteropus bats of a paramyxovirus related to equine morbillivirus. Emerg Infect Dis. 1996;2:23940. DOIPubMedGoogle Scholar
  10. Feiden  W, Kaiser  E, Gerhard  L, Dahme  E, Gylstorff  B, Wandeler  A, Immunohistochemical staining of rabies virus antigen with monoclonal and polyclonal antibodies in paraffin tissue sections. Zentralbl Veterinarmed [C]. 1988;35:24755.
  11. Smith  JS, Yager  PA, Baer  GM. A rapid tissue culture test for determining rabies neutralising antibody. In: Kaplan MM and Koprowski H, editors. Laboratory Techniques in Rabies, 3rd ed. Geneva, Switzerland: World Health Organization, 1973.
  12. Bouhry  H, Kissi  B, Tordo  N. Molecular diversity of the Lyssavirus genus. Virology. 1993;194:7081. DOIPubMedGoogle Scholar
  13. Kissi  B, Tordo  M, Bourhy  H. Genetic polymorphism in the rabies virus nucleoprotein gene. Virology. 1995;209:52637. DOIPubMedGoogle Scholar
  14. Wiktor  TJ, Koprowski  H. Antigenic variants of rabies virus. J Exp Med 1980;152:99-111.15
  15. Smith  JS. Rabies virus epitopic variation: use in ecologic studies. Adv Virus Res. 1989;36:21553. DOIPubMedGoogle Scholar
  16. Fekadu  M, Shaddock  JH, Sanderlin  DW, Smith  JS. Efficacy of rabies vaccines against Duvenhage virus isolated from European house bats (Eptesicus serotinus), classic rabies and rabies-related viruses. Vaccine. 1988;6:5339. DOIPubMedGoogle Scholar

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