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Volume 2, Number 4—October 1996
Dispatch

Assessing the Costs and Benefits of an Oral Vaccine for Raccoon Rabies: A Possible Model

Martin I. Meltzer
Author affiliation: Centers for Disease Control and Prevention, Atlanta, Georgia, USA

Main Article

Table 2

Net present values (NPV) of different distribution scenarios for using an oral vaccine to control raccoon rabies

Baiting scenario NPV without pet vaccination ($ millions)
 NPV with pet vaccinationsa 
($ millions)
Discount rate
 Discount rate
0% 3% 5% 0% 3% 5%
Expanding circlesb -10.2 -6.2 -4.7 +5.5 +3.1 +2.2
Entire area at onceb -21.3 -15.7 -13.3 -0.5 -1.1 -1.3
 
Sensitivity analyses
Reduced distribution:savingsc
Expanding circles -14.3 -8.5 -6.3 +1.4 +0.9 +0.6
Entire area done at once -30.8 -21.9 -18.2 -12.5 -8.9 -7.3
No baiting of boundary
Expanding circles -0.7 -1.8 -2.1 +14.1 +7.9 +4.5
Entire area at once +2.9 -0.9 -2.3 +23.7 +13.7 +9.7

a) Cost savings (benefits) of 11 pets/sq. mi during an epizootic period, and 2.75 pets/sq. mi during the post-epizootic period, both at $16/pet.
b) Expanding circles assumes start with 20-mi radius, expanding by 5 mi every 2 years for 20 years, and then baiting a 5-mi wide boundary for next 10 years. Entire area assumes baiting 65-mi radius for 2 years, followed by 28 years of baiting 5-mi wide radius.
c) Ratio of distribution costs:cost savings is 1:1.03,based on New Jersey data (1). In baseline scenario, ratio is 1:1.57.

Main Article

References
  1. Rupprecht  CE, Smith  JS. Raccoon rabies—the re-emergence of an epizootic in a densely populated area. Semin Virol. 1994;5:155–64. DOIGoogle Scholar
  2. Krebs  JW, Strine  TW, Smith  JS, Rupprecht  CE, Childs  JE. Rabies surveillance in the United States during 1993. J Am Vet Med Assoc. 1994;205:1695–709.PubMedGoogle Scholar
  3. Centers for Disease Control and Prevention. Rabies postexposure prophylaxis—Connecticut, 1990-1994. MMWR Morb Mortal Wkly Rep. 1996;45:232–4.PubMedGoogle Scholar
  4. Centers for Disease Control and Prevention. Animal rabies—South Dakota, 1995. MMWR Morb Mortal Wkly Rep. 1996;45:164–6.PubMedGoogle Scholar
  5. Uhaa  IJ, Dato  VM, Sorhage  FE, Beckly  JW, Roscoe  DE, Gorsky  RD, Benefits and costs of using an orally absorbed vaccine to control rabies in raccoons. J Am Vet Med Assoc. 1992;201:1873–82.PubMedGoogle Scholar
  6. Winkler  WG, Bogel  K. Control of rabies in wildlife. Sci Am. 1992; (June):86–92. DOIPubMedGoogle Scholar
  7. Rupprecht  CE, Smith  JS, Fekadu  M, Childs  JE. The ascension of wildlife rabies: A cause for public health concern or intervention? Emerg Infect Dis. 1995;1:107–14. DOIPubMedGoogle Scholar
  8. Steck  F, Wandler  A, Bischel  P, Capt  S, Hafliger  U, Schneider  L. Oral immunization of foxes against rabies. Laboratory and field studies. Comp Immunol Microbiol Infect Dis. 1982;5:165–79. DOIPubMedGoogle Scholar
  9. Rupprecht  CE, Wiktor  TJ, Johnson  DH, Hamir  AN, Dietzschold  B, Wunner Wh, et al. Oral immunization and protection of raccoons (Procyon lotor) with a vaccinia-rabies glycoprotein recombinant virus vaccine. Proc Natl Acad Sci U S A. 1986;83:7947–50. DOIPubMedGoogle Scholar
  10. Robbins  AH, Niezgoda  M, Levine  S, Windmiller  BS, McGuill  MW, Rowell  SL, Oral rabies vaccination of raccoons (Procyon lotor) on the Cape Cod isthmus, Massachusetts. Presented at the 5th Annual International Meeting of Rabies in the Americas, Niagara Falls, Ontario, Canada, 1994; Conference Abstracts, p.29.
  11. Hanlon  CA, Trimarchi  CE, Rupprecht  CE, Debbie  JG. Oral wildlife rabies vaccination in New York state: First field evaluation in an enzootic raccoon rabies area. Presented at the 6th Annual International Meeting on Research Advances and Rabies Control in the Americas, Merida, Mexico, 1995; Program and Abstracts, p.29.
  12. Manning  A. Texas officials take battle against rabies to the air. USA Today January 11, 1996:27.
  13. Slate  D, Calvert  RT, Chipman  RB, Barden  ME. Raccoon pest management patterns before, during and after a rabies epizootic in northern New England: What do they mean? Presented at the 6th Annual International Meeting on Research Advances and Rabies Control in the Americas, Merida, Mexico; 1995; Program and Abstracts, p.20.
  14. Gold  MR, Siegel  JE, Russell  LB, Weinstein  MC, eds. Cost effectiveness in health and medicine. New York: Oxford University Press, 1996.
  15. Haddix  AC, Teutsch  SM, Shaffer  PA, Dunet  DO, eds. Prevention effectiveness: A guide to decision analysis and economic evaluation. New York: Oxford University Press, 1996.
  16. Perry  BD, Garner  N, Jenkins  SR, McCloskey  K, Johnston  DH. A study of techniques for the distribution of oral rabies vaccine to wild raccoon populations. J Wildl Dis. 1989;25:206–17.PubMedGoogle Scholar
  17. Linhart  SB, Blom  FS, Engeman  RM, Hill  HL, Hon  T, Hall  DI, A field evaluation of baits for delivering oral rabies vaccines to raccoons (Procyon lotor). J Wildl Dis. 1994;30:185–94.PubMedGoogle Scholar
  18. Hanlon  CL, Hayes  DE, Hamir  AN, Snyder  DE, Jenkins  S, Hable  CP, Proposed field evaluation of a rabies recombinant vaccine for raccoons (Procyon lotor): sites election, target species characteristics, and placebo baiting trials. J Wildl Dis. 1989;25:555–67.PubMedGoogle Scholar
  19. Hoffmann  CO, Gottschang  JL. Numbers, distribution, and movements of a raccoon population in a suburban residential community. J Mammal. 1977;58:623–36. DOIGoogle Scholar
  20. Hudson  EM. The raccoon (Procyon lotor) on St. Catherines Island, Georgia: Part 2: Relative abundance in different forest types as a function of population density. American Musgum Novitates 1978;1-16.
  21. Population Estimates and Population Distribution Branches, Division of Population, U.S. Bureau of the Census. Estimates of the resident population of states and counties, and percent change 4/1/90 to 7/1/94. Posted on the Internet: 1995 Jan 18.
  22. American Veterinary Medical Association. US pet ownership and demographics source book. Schaumburg, IL: American Veterinary Medical Association, 1995.

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The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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