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Volume 20, Number 1—January 2014
Synopsis

Severe Fever with Thrombocytopenia Syndrome, Shandong Province, China, 2011

Hong-Ling Wen1, Li Zhao1, Shenyong Zhai, Yuanyuan Chi, Feng Cui, Dongxu Wang, Ling Wang, Zhiyu Wang, Qian Wang, Shoufeng Zhang, Yan Liu, Hao Yu, and Xue-Jie YuComments to Author 
Author affiliations: Shandong University School of Public Health, Jinan, China (H.-L. Wen. L. Zhao, Y. Chi, D. Wang, Z. Wang, X.-J. Yu); Zibo Municipal Center for Disease Control and Prevention, Zibo, China (S. Zhai, F. Cui, L. Wang); Yiyuan County Center for Disease Control and Prevention, Yiyuan, China (Q. Wang, S. Zhang); University of Texas Medical Branch, Galveston, Texas, USA (Y. Liu, H. Yu, X.-J. Yu)

Main Article

Table 3

Detection of SFTSV RNA and virus-specific antibody in serum samples of 24 patients, Shandong Province, China, 2011*

Patient no. or parameter
 Day of blood collection after disease onset
 Acute-phase serum samples, n = 24
Convalescent-phase serum samples, n = 21 RT-PCR– or ELISA–confirmed SFTSV cases, n = 24
RT-PCR, S RNA segment
 ELISA titer
 ELISA titer
1 5 – 2 0 +
2 10 + 64 ND +
3 6 – 0 64 +
4 4 – 0 0 –
5 9 – 256 ≥512 +
6 7 + 0 ≥512 +
7 4 +† 0 128 +
8 13 – 0 128 +
9 5 – 0 0 –
10 7 +† 0 256 +
11 6 – 0 256 +
12 6 + 64 ≥512 +
13 7 +† 0 ≥512 +
14 5 – 256 ≥512 +
15 4 +† 0 ≥512 +
16 10 + 0 ND +
17 6 + 32 128 +
18 13 – 512 NA +
19 10 – 64 256 +
20 10 – 256 256 +
21 7 + 512 256 +
22 6 + 32 ≥512 +
23 8 + 32 32 +
24
 6
 –
 64
256
 +
SFTSV positivity rate, % NA 50 54 86 92
Sensitivity, % NA 55 59 95 NA

* SFTSV positivity rate was calculated by using patients given a clinical diagnosis (n = 24) as the denominator. Sensitivity was calculated by using laboratory-confirmed cases (n = 22) as the denominator. SFTSV, severe fever with thrombocytopenia syndrome virus; RT-PCR, reverse transcription PCR; S, small; –, negative; +, positive; ND, not determined; NA, not applicable.
†Positive by RT-PCR for S and large segments.

Main Article

1These authors contributed equally to this article.

Page created: January 03, 2014
Page updated: January 03, 2014
Page reviewed: January 03, 2014
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