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Volume 20, Number 2—February 2014
Research

Novel Paramyxovirus Associated with Severe Acute Febrile Disease, South Sudan and Uganda, 2012

César G. Albariño, Michael Foltzer, Jonathan S. Towner, Lory A. Rowe, Shelley Campbell, Carlos M. Jaramillo, Brian H. Bird, DeeAnn M. Reeder, Megan E. Vodzak, Paul Rota, Maureen G. Metcalfe, Christina F. Spiropoulou, Barbara Knust, Joel P. Vincent, Michael A. Frace, Stuart T. Nichol, Pierre E. Rollin, and Ute StröherComments to Author 
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (C.G. Albariño, J.S. Towner, L.A. Rowe, S. Campbell, B.H. Bird, P. Rota, M.G. Metcalfe, C.F. Spiropoulou, B. Knust, J.P. Vincent, M.A. Frace, S.T. Nichol, P.E. Rollin, U. Ströher); Geisinger Medical Center, Danville, Pennsylvania, USA (M. Foltzer, C.M. Jaramillo); Bucknell University, Lewisburg, Pennsylvania, USA (D.M. Reeder, M.E. Vodzak)

Main Article

Table

Vital signs and laboratory results for patient infected with a novel paramyxovirus related to rubula-like viruses isolated from fruit bats

DSO DH Max temp Max pulse SBP WBC Plate Creat AST ALT LDH, TB PT/INR ratio TG Ferr qRT-PCR, Ct† IgM ELISA† IgG ELISA†
2 1 40.1 90 112 1.62 115 0.8 93 19 687 0.2
3 2 40.1 79 112 1.53 93 0.7 133 20 0.1 17.2/1.45 29.5 <50 <50
4 3 40.4 77 103 1.06 77 0.6 164 28 0.1 15.8/1.29 120
5 4 1.02 65 0.7 319 134 0.1 13.6/1.06 17,840
6 5 38.6 77 102 0.95 62 0.6 615 261 0.1 13.7/1.07 127 11,595
7 6 1.46 79 0.6 589 298 0.2 14.4/1.14 7,309
8 7 1.64 84 0.5 516 299 0.1 15.5/1.26 3,371
9 8 0.96 123 0.5 342 259 0.1 16.9/1.41 36.3 >1,600 >1,600
10 9 1.20 154 0.4 170 186 0.1 17.4/1.47 36.9 >1,600 >1,600
11 10 2.19 222 0.4 185 188 0.1 14.7/1.18 Neg >1,600 >1,600
12 11 2.61 220 0.4 107 149 0.2 13.2/1.02 Neg >1,600 >1,600
13 12 5.62 335 0.4 Neg
14 13 5.79 387 0.4 Neg
15 14 36.8 67 98 4.71 437 0.5 212 Neg >1,600 >1,600
30 3.71 221 19 15 0.3
60 5.44 348 12.4 Neg >400 >1,600

*Shading indicates values outside reference range; blank cells indicate data not obtained. DSO, days from symptom onset; DH, day of hospitalization; max temp, maximum temperature, °C; max pulse; maximum pulse rate, beats/minute; SBP, systolic blood pressure, mm Hg; WBC, leukocytes ,× 1,000/µL; plate, platelets × 1,000/µL; creat, creatinine, mg/dL; AST, aspartate aminotransferase, IU/L; ALT, alanine aminotransferase, IU/L; LDH, lactate dehydrogenase, IU/L; TB, total bilirubin, mg/dL; PT/INR, prothrombin time/international normalized ratio; TG, triglycerides, g/dL; ferr, ferritin, ng/mL; qRT-PCR, quantitative reverse transcription PCR; Ct, cycle threshold; neg, negative.
†Assays were developed after the virus genome was determined.

Main Article

Page created: January 15, 2014
Page updated: January 15, 2014
Page reviewed: January 15, 2014
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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