Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 20, Number 4—April 2014
Dispatch

Genetic Characterization of Clade 2.3.2.1 Avian Influenza A(H5N1) Viruses, Indonesia, 2012

Ni Luh Putu Indi DharmayantiComments to Author , Risza Hartawan, Pudjiatmoko, Hendra Wibawa, Hardiman, Amanda Balish, Ruben Donis, C. Todd Davis, and Gina Samaan
Author affiliations: Indonesian Research Center for Veterinary Science, Bogor, Indonesia (N.L.P.I. Dharmayanti, R. Hartawan, Hardiman); Ministry of Agriculture, Jakarta, Indonesia (Pudjiatmoko); Disease Investigation Center Wates, Jogjakarta, Indonesia (H. Wibawa); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (A. Balish, R. Donis, C.T. Davis); Centers for Disease Control and Prevention, Jakarta (G. Samaan)

Main Article

Table 1

Genetic characteristics of influenza A(H5N1) clade 2.3.2.1 viruses found in Indonesia, 2012*†

Strain name PB2
 PB1-F2
 HA‡
 NA
 M2
 NS sequence
aa 627 aa 701 PB1-F2 truncation aa 66 aa 222 aa 224 Cleavage site aa 203 aa 27 aa 31 aa 80–84 del PDZ binding ligand
A/Hubei/1/2010 E D 90 aa N Q G PQRERRRKR↓G I I S Yes ESEV
A/Hong Kong/
6841/2010 E D 90 aa N Q G PQRERRRKR↓G I I S Yes ESEV
A/env/East Java/ LBM-LM13/2012 E D 57 aa N Q G PQRERRRKR↓G V I S Yes ESEV
A/duck/Sukoharjo/ BBVW-1428–9/2012 E D 57 aa N Q G PQRERRRKR↓G I I S Yes ESEV
A/duck/Bantul/ BBVW-1443-9/2012 E D 57 aa N Q G PQRERRRKR↓G I I S Yes ESEV
A/duck/Sleman/ BBVW-1463–10/2012 E D 57 aa N Q G PQRERRRKR↓G ND I S Yes ESEV
A/md/Tegal/
BBVW-1732-11/2012 ND ND ND ND Q G PQRERRRKR↓G ND ND ND ND ND
A/dk/Blitar/
BBVW-1731-11/2012 ND ND ND ND Q G PQRERRRKR↓G ND ND ND ND ND
A/dk/Tegal/
BBVW-1727-11/2012 ND ND ND ND Q G PQRERRRKR↓G ND ND ND ND ND
A/dk/Wonogiri/
BBVW-1730-11/2012 ND ND ND ND Q G PQRERRRKR↓G ND ND ND ND ND

*HA, hemagluttinen; NA, neuraminidase; M2, matrix 2; NS, nonstructural; ND, not determined.
†Numbering of the first and last nucleotide position of the gene that was sequenced is as follows: PB2, 1618–2192; PB1, 130–632; PA, 34–429; HA, 1–1710; NP, 268–755; NA, 55–1314; M, 55–919; NS, 25–690.
‡Glycosylation motif at 154 was absent for all strains.

Main Article

Page created: March 20, 2014
Page updated: March 20, 2014
Page reviewed: March 20, 2014
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external