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Volume 20, Number 5—May 2014
Dispatch

Influenza A(H5N2) Virus Antibodies in Humans after Contact with Infected Poultry, Taiwan, 2012

Ho-Sheng Wu, Ji-Rong Yang, Ming-Tsan Liu, Chin-Hui Yang, Ming-Chu Cheng, and Feng-Yee ChangComments to Author 
Author affiliations: Centers for Disease Control, Taipei, Taiwan (H.-S. Wu, J.-R. Yang, M.-T. Liu, C.-H. Yang, F.-Y. Chang); Taipei Medical University, Taipei (H.-S. Wu); Animal Health Research Institute, Taipei (M.-C. Cheng); National Defence Medical Center, Taipei (F.-Y. Chang)

Main Article

Table 2

Serologic test results and vaccination and occupational histories for persons who had high antibody titers against influenza A(H5N2) virus and contact with infected poultry, Taiwan, 2012*†

Cont. no. Sample date Tested antigens, by influenza subtype
 NS1-ELISA titer
 Date and type of influenza vaccination
 Occupation
H5N2
 H5N1
 H1N1pdm09
 H3N2
HI MN HI NS1-pA NS1-pB A(H5N1) Seasonal
1 Mar 3 40 <20 80 <10 10 1.68 1.4 2012 Mar 3, 30 NA Poultry worker
Mar 30 80 230 80 <10 10
2 Mar 5 40 160 40 20 80 0.89 0.86 2012 Mar 6, 28 2011 Oct 8 Poultry worker
Mar 28 160 450 80 20 80
3 Mar 5 40 20 80 20 40 1.70 1.34 2012 Mar 5 2012 Jan 20 Animal health official
Mar 27 80 80 80 20 40
4 Mar 5 40 <20 40 10 40 1.13 1.09 2012 Mar 5, Apr 2 2012 Jan 20 Animal health official
Apr 2 80 80 40 10 40
5 Mar 6 40 20 40 <10 320 1.21 1.02 2012 Mar 6, Apr 2 2011 Nov 26 Temp. employee
Apr 2 80 30 40 <10 160
6 Mar 6 20 <20 40 <10 160 1.17 1.08 2012 Mar 6, Apr 2 2012 Mar 5 Temp. employee
Apr 2 80 160 80 <10 640
7 Mar 5 40 <20 40 <10 40 0.98 1.05 2012 Mar 5, Apr 2 2012 Mar 5 Temp. employee
Apr 2 320 1,280 160 10 640

*Cont., contact; HI, hemagglutination inhibition; MN, microneutralization; NS1, nonstructural protein 1; H1N1pdm09, pandemic influenza A(H1N1); NA, not applicable (did not receive vaccination); temp., temporary.
†Boldface indicates a >4-fold rise in antibody titer by HI or MN tests and a positive anti-NS1 antibody response by NS1-ELISA test between the first and second samples of paired serum samples. A positive anti-NS1 antibody response by NS1-ELISA assay was defined as each paired serum sample having a test absorbance of the second sample 30% higher than that of its first sample (ratio >1.30).

Main Article

Page created: April 17, 2014
Page updated: April 17, 2014
Page reviewed: April 17, 2014
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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