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Volume 20, Number 6—June 2014
Dispatch

New Hepatitis E Virus Genotype in Camels, the Middle East

Patrick C.Y. Woo1Comments to Author , Susanna K.P. Lau1, Jade L.L. Teng1, Alan K. L. Tsang1, Marina Joseph, Emily Y.M. Wong, Ying Tang, Saritha Sivakumar, Jun Xie, Ru Bai, Renate Wernery, Ulrich Wernery, and Kwok-Yung Yuen
Author affiliations: State Key Laboratory of Emerging Infectious Diseases, Hong Kong, China (P.C.Y. Woo, S.K.P. Lau, K.-Y. Yuen); The University of Hong Kong, Hong Kong (P.C.Y. Woo, S.K.P. Lau, J.L.L. Teng, A.K.L. Tsang, E.Y.M. Wong, Y. Tang, J. Xie, R. Bai, K.-Y. Yuen); Central Veterinary Research Laboratory, Dubai, United Arab Emirates (M. Joseph, S. Sivakumar, R. Wernery, U. Wernery)

Main Article

Table

Comparison of genomic organization of HEV genotypes and isolates*

HEV (GenBank accession no.)
 Genome length, nt
 GC content, %
 5′ UTR, nt
 ORF1, aa
 ORF2, aa
 ORF3, aa
 3′ UTR, nt
DcHEV-178C (KJ496143)† 7,220 55.1 39 1,698 660 113 66
DcHEV-180C (KJ496144)‡ 7,219 54.4 39 1,698 660 113 66
HEV1 (M73218) 7,194 58.1 27 1,693 660 114 65
HEV2 (M74506)ठ>7,170 56.5 NA 1,691 659 114 74
HEV3 (AB089824) 7,244 55.3 25 1,709 660 113 72
HEV4 (AJ272108) 7,232 54.4 25 1,707 658 112 68
Rabbit HEV (FJ906895)‡ 7,283 55.5 26 1,722 660 113 71
Germany rat HEV (GU345042) 6,948 57.8 10 1,636 644 102 65
Vietnam rat HEV (JX120573) 6,927 56.6 10 1,629 644 102 65
Ferret HEV (JN998606) 6,841 53.8 12 1,596 654 108 65
Wild boar HEV novel unclassified genotype (AB602441) 7,246 57.0 25 1,709 660 112 70
Bat HEV (JQ001749) 6,767 51.8 33 1,580 637 137 77
Avian HEV genotype 1 (AM943647)§ >6,627 55.1 NA >1,531 606 87 123
Avian HEV genotype 2 (AY535004) 6,654 55.5 24 1,531 606 87 127
Avian HEV genotype 3 (AM943646§ >6,631 55.6 NA 1,532 606 87 126
Avian HEV novel unclassified genotype (JN997392)§ >6,543 55.7 NA >1,515 606 87 NA
Cutthroat trout HEV (HQ731075) 7,269 49.7 100 1,707 634 225 76

*HEV, hepatitis E virus; UTR, untranslated region; ORF, open reading frame; DcHEV HEV from dromedary camel; NA, not available because of incomplete genome.
†Assuming the third AUG of ORF2 is the start codon.
‡Assuming the third AUG of ORF3 is the start codon.
§Near-complete genome.

Main Article

1These authors contributed equally to this article.

Page created: May 16, 2014
Page updated: May 16, 2014
Page reviewed: May 16, 2014
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