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Volume 20, Number 7—July 2014

Borrelia miyamotoi sensu lato Seroreactivity and Seroprevalence in the Northeastern United States

Peter J. KrauseComments to Author , Sukanya Narasimhan, Gary P. Wormser, Alan G. Barbour, Alexander E. Platonov, Janna Brancato, Timothy Lepore, Kenneth Dardick, Mark Mamula, Lindsay Rollend, Tanner K. Steeves, Maria Diuk-Wasser, Sahar Usmani-Brown, Phillip Williamson, Denis S. Sarksyan, Erol Fikrig, Durland Fish, and the Tick Borne Diseases Group
Author affiliations: Yale School of Public Health, New Haven, Connecticut, USA (P.J. Krause, J. Brancato, L. Rollend, T.K. Steeves, M. Diuk-Wasser, D. Fish); Yale School of Medicine, New Haven (P.J. Krause, S. Narasimhan, M. Mamula, E. Fikrig); New York Medical College, Valhalla, New York, USA (G.P. Wormser); University of California, Irvine, California, USA (A.G. Barbour); Central Research Institute of Epidemiology, Moscow, Russia (A.E. Platonov); Nantucket Cottage Hospital, Nantucket, Massachusetts, USA (T. Lepore); Mansfield Family Practice, Mansfield, Connecticut, USA (K. Dardick); L2 Diagnostics, LLC, New Haven (S. Usmani-Brown); Creative Testing Solutions, Tempe, Arizona, USA (P. Williamson); State Medical Academy, Izhevsk, Russia (D.S. Sarksyan)

Main Article

Table 2

Number of false-positive Borrelia burgdorferi assay results for participants in various relapsing fever studies*

Borrelia burgdorferi assay No. participants seroreactive to B. burgdorferi/no. total (%)
B. miyamotoi (current study)�? B. hermsii (23) B. hermsii (24) B. recurrentis (24) B. recurrentis (25)
Whole-cell sonicate ELISA 7/36 (19) ND 7/11 (64) 3/11 (27) 5�?"7/11 (45�?"64)
C6 ELISA 6/35 (17)�?� 1/14 (7) ND ND ND
Whole-cell sonicate ELISA and Western blot 4/36 (11) 2/14 (14) ND ND ND

* ND, not determined.�?"�? Study participants had no history of Lyme disease within the 2 years before serum was obtained for testing.�?"�?�The quantity of 1 serum sample was insufficient to test.

Main Article

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Main Article

1Members of the Tick Borne Diseases Group are listed at the end of this article.

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