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Volume 20, Number 9—September 2014
Dispatch

Family Cluster of Middle East Respiratory Syndrome Coronavirus Infections, Tunisia, 2013

Fekri AbrougComments to Author , Amine Slim, Lamia Ouanes-Besbes, Mohamed-Ali Hadj Kacem, Fahmi Dachraoui, Islem Ouanes, Xiaoyan Lu, Ying Tao, Clinton Paden, Hayat Caidi, Congrong Miao, Mohammed Mohammed Al-Hajri, Mokhtar Zorraga, Wissem Ghaouar, Afif BenSalah, Susan I. Gerber, and World Health Organization Global Outbreak Alert and Response Network Middle East Respiratory Syndrome Coronavirus International Investigation Team
Author affiliations: Centre Hospitalier-Universitaire Fattouma Bourguiba, Monastir, Tunisia (F. Abroug, L. Ouanes-Besbes, F. Dachraoui, I. Ouanes); Centre Hospitalier-Universitaire Charles Nicolle, Tunis, Tunisia (A. Slim, M.-A. Hadj Kacem); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (X. Lu, Y. Tao, C. Paden, H. Caidi, C. Miao, S.I. Gerber); Supreme Council of Health, State of Qatar (M. Mohammed Al-Hajri); Direction des Soins de Santé de Base, Tunis (M. Zorraga, W. Ghaouar, A. BenSalah)

Main Article

Figure 2

Midpoint-rooted phylogenetic trees of the full-length nucleocapsid (N) (panel A) and spike (S) (panel B) open-reading frames (ORFs) of isolates obtained from index case-patient with Middle East respiratory syndrome coronavirus (MERS-CoV) infection, Tunisia, 2013. Serum and available nucleotide sequences from GenBank and Public Health England (http://www.hpa.org.uk/webw/HPAweb&HPAwebStandard/HPAweb_C/1317136246479) and the Institut Für Virologie (http://www.virology-bonn.de/index.php?id = 46)

Figure 2. Midpoint-rooted phylogenetic trees of the full-length nucleocapsid (N) (panel A) and spike (S) (panel B) open-reading frames (ORFs) of isolates obtained from index case-patient with Middle East respiratory syndrome coronavirus (MERS-CoV) infection, Tunisia, 2013. Serum and available nucleotide sequences from GenBank and Public Health England (http://www.hpa.org.uk/webw/HPAweb&HPAwebStandard/HPAweb_C/1317136246479) and the Institut Für Virologie (http://www.virology-bonn.de/index.php?id = 46). The estimated neighbor-joining trees were constructed from nucleotide alignments by using MEGA version 6.06 (http://www.megasoftware.net). Sequence names are written as GenBank accession number|virus strain name|month-year of collection. Numbers in parentheses denote the number of additional sequences from viruses isolated from humans that are identical to the listed sequence. Solid circles indicate sequences from MERS-CoV from Tunisia, 2013. Camel icons indicate MERS-CoV sequences derived from isolates from camels. Bootstrap support values (1,000 replicates) ≥75% were plotted at the indicated internal branch nodes. Scale bars indicate number of nucleotide substitutions per site.

Main Article

1Team members: Philippe Barboza, Alison Bermingham, Julie Fontaine, Alireza Mafi, Babakar Ndoya, and Nahoko Shindo.

Page created: August 14, 2014
Page updated: August 14, 2014
Page reviewed: August 14, 2014
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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