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Volume 21, Number 11—November 2015

Neurologic Disorders in Immunocompetent Patients with Autochthonous Acute Hepatitis E

H. Blasco Perrin, P. Cintas, F. Abravanel, R. Gérolami, L. d'Alteroche, J.-N. Raynal, L. Alric, E. Dupuis, L. Prudhomme, E. Vaucher, P. Couzigou, J.-M. Liversain, C. Bureau, J.-P. Vinel, N. Kamar, J. Izopet, and J.-M. Peron
Author affiliations: Hôpital Purpan–CHU Toulouse, Toulouse, France (H. Blasco Perrin, P. Cintas, F. Abravanel, L. Alric, C. Bureau, J.-P. Vinel, J. Izopet, J.M. Peron); Hôpital de La Conception–CHU Marseille, Marseille, France (R. Gérolami); Hôpital Trousseau–CHU Tours, Tours, France (L. d'Alteroche); Clinique de l’Union, l’Union, France (J.-N. Raynal); Clinique Pasteur, Toulouse (E. Dupuis); CHIC Castres-Mazamet, Castres-Mazamet, France (L. Prudhomme); CH Narbonne, Narbonne, France (E. Vaucher); Hôpital du Haut-Lévêque–CHU Bordeaux, Bordeaux, France (P. Couzigou); CH Mont de Marsan, Mont de Marsan, France (J.-M. Liversain); Hôpital Ranguei–CHU Toulouse, Toulouse (L. Buscail, N. Kamar)

Main Article

Table 1

Clinical characteristics of 15 patients with hepatitis E virus–linked neurologic disorders, France, January 2006–June 2013*

Patient no. Neurologic pathology Age, y/sex Treatment Other symptoms Neurologic symptoms at last follow-up Follow up times, wk
1 MM 59/M None Asthenia No 10
2 MM 44/F None Fever, asthenia, arthromyalgia Yes 4
3 MM 65/M Corticosteroids Asthenia No 157
4 MM 25/F None None No 33
5 MM 49/M None None No NA
6 MM 77/F RBV None No 44
7 PTS 51/M RBV + IVIg Arthromyalgia, asthenia No 100
8 PTS 55/F None Asthenia, arthromyalgia Yes 126
9 PTS 56/M None Asthenia Yes 42
10 PTS 56/M RBV + IVIg Asthenia Yes 16
11 MR 74/M IV Ig Arthromyalgia, asthenia No 77
12 MR 54/F None Fever, nausea No NA
13 MR 33/F None Fever, arthromyalgia No 161
14 GBS 60/F IV Ig Asthenia, acute low back pain Yes 5
15 MFS 54/M IV Ig Asthenia, anorexia Yes 13

*MM, mononeuritis multiplex; PTS, Parsonnage-Turner syndrome; MR, meningoradiculitis; GBS, Guillain–Barré syndrome; MFS, Miller-Fisher syndrome; RBV, ribavirin; IVIg, intravenous immunoglobulin; NA, not available.

Main Article

Page created: October 19, 2015
Page updated: October 19, 2015
Page reviewed: October 19, 2015
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