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Volume 21, Number 11—November 2015
CME ACTIVITY - Synopsis

Neurologic Disorders in Immunocompetent Patients with Autochthonous Acute Hepatitis E

H. Blasco Perrin, P. Cintas, F. Abravanel, R. Gérolami, L. d'Alteroche, J.-N. Raynal, L. Alric, E. Dupuis, L. Prudhomme, E. Vaucher, P. Couzigou, J.-M. Liversain, C. Bureau, J.-P. Vinel, N. Kamar, J. Izopet, and J.-M. Peron
Author affiliations: Hôpital Purpan–CHU Toulouse, Toulouse, France (H. Blasco Perrin, P. Cintas, F. Abravanel, L. Alric, C. Bureau, J.-P. Vinel, J. Izopet, J.M. Peron); Hôpital de La Conception–CHU Marseille, Marseille, France (R. Gérolami); Hôpital Trousseau–CHU Tours, Tours, France (L. d'Alteroche); Clinique de l’Union, l’Union, France (J.-N. Raynal); Clinique Pasteur, Toulouse (E. Dupuis); CHIC Castres-Mazamet, Castres-Mazamet, France (L. Prudhomme); CH Narbonne, Narbonne, France (E. Vaucher); Hôpital du Haut-Lévêque–CHU Bordeaux, Bordeaux, France (P. Couzigou); CH Mont de Marsan, Mont de Marsan, France (J.-M. Liversain); Hôpital Ranguei–CHU Toulouse, Toulouse (L. Buscail, N. Kamar)

Main Article

Table 1

Clinical characteristics of 15 patients with hepatitis E virus–linked neurologic disorders, France, January 2006–June 2013*

Patient no. Neurologic pathology Age, y/sex Treatment Other symptoms Neurologic symptoms at last follow-up Follow up times, wk
1 MM 59/M None Asthenia No 10
2 MM 44/F None Fever, asthenia, arthromyalgia Yes 4
3 MM 65/M Corticosteroids Asthenia No 157
4 MM 25/F None None No 33
5 MM 49/M None None No NA
6 MM 77/F RBV None No 44
7 PTS 51/M RBV + IVIg Arthromyalgia, asthenia No 100
8 PTS 55/F None Asthenia, arthromyalgia Yes 126
9 PTS 56/M None Asthenia Yes 42
10 PTS 56/M RBV + IVIg Asthenia Yes 16
11 MR 74/M IV Ig Arthromyalgia, asthenia No 77
12 MR 54/F None Fever, nausea No NA
13 MR 33/F None Fever, arthromyalgia No 161
14 GBS 60/F IV Ig Asthenia, acute low back pain Yes 5
15 MFS 54/M IV Ig Asthenia, anorexia Yes 13

*MM, mononeuritis multiplex; PTS, Parsonnage-Turner syndrome; MR, meningoradiculitis; GBS, Guillain–Barré syndrome; MFS, Miller-Fisher syndrome; RBV, ribavirin; IVIg, intravenous immunoglobulin; NA, not available.

Main Article

Page created: October 19, 2015
Page updated: October 19, 2015
Page reviewed: October 19, 2015
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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