Volume 21, Number 11—November 2015
Dispatch
Epidemiology of Primary Multidrug-Resistant Tuberculosis, Vladimir Region, Russia
Table
Association between sociodemographic and clinical characteristics of persons with newly diagnosed cases of non–MDR TB and MDR TB, Vladimir Region, Russia, 2012*
Characteristic | Total, n = 191 | MDR TB, n = 44 | Non–MDR TB, n = 147 | Prevalence ratio | 95% CI | p value |
---|---|---|---|---|---|---|
Sex | ||||||
Male | 146 (74.4) | 34 (77.3) | 112 (76.2) | 1.05 | 0.56–1.95 | 0.88 |
Female |
45 (23.6) |
10 (22.7) |
35 (23.8) |
Referent |
||
Median age, y (interquartile range)† |
39 (30–49) |
36 (30–46) |
40 (30–50) |
0.34‡ |
||
HIV† | ||||||
Positive | 18 (9.6) | 7 (16.3) | 11 (7.6) | 1.8 | 0.96−3.51 | 0.09 |
Negative |
170 (90.4) |
36 (83.7) |
134 (92.4) |
Referent |
||
Health care worker | ||||||
Yes | 2 (1.1) | 1 (2.3) | 1 (0.7) | 2.2 | 0.54–9.01 | 0.27 |
No |
189 (98.9) |
43 (97.7) |
146 (99.3) |
Referent |
||
Homelessness | ||||||
Yes | 11(5.8) | 4 (9.1) | 7 (4.8) | 1.64 | 0.72−3.75 | 0.24 |
No |
180 (94.2) |
40 (90.9) |
140 (95.2) |
Referent |
||
Employment | ||||||
Employed | 42 (22.0) | 10 (22.7) | 32 (21.8) | Referent | ||
Unemployed | 114 (59.7) | 25 (56.8) | 89 (60.5) | 0.92 | 0.48–1.75 | 0.80 |
Not working§ |
35 (18.3) |
9 (20.5) |
26 (17.7) |
1.08 |
0.49–2.35 |
0.85 |
History of imprisonment ¶ | ||||||
Yes | 51(26.8) | 10 (22.7) | 41 (28.1) | 0.8 | 0.43–1.50 | 0.49 |
No |
139 (73.2) |
34 (77.3) |
105 (71.9) |
Referent |
||
Alcohol abuse | ||||||
Yes | 35 (18.3) | 9 (20.5) | 26 (17.8) | 1.15 | 0.61–2.16 | 0.67 |
No |
156 (81.7) |
35 (79.5) |
121 (82.3) |
Referent |
||
Illicit drugs use# | ||||||
Yes | 12 (6.3) | 3 (7.0) | 9 (6.2) | 1.11 | 0.40–3.06 | 0.85 |
No |
177 (93.7) |
40 (3.05) |
137 (93.8) |
Referent |
||
Diabetes¶ | ||||||
Yes | 13 (6.8) | 3 (7.0) | 10(6.8) | 1.02 | 0.36–2.86 | 0.97 |
No |
177 (93.2) |
40 (93.0) |
137 (93.2) |
Referent |
||
Contact with TB patient | ||||||
Yes | 55 (28.8) | 16 (36.4) | 39 (26.5) | 1.45 | 0.85–2.49 | 0.17 |
No | 130 (68.1) | 26 (59.1) | 104 (70.7) | Referent | ||
Unknown |
6 (3.1) |
2 (4.5) |
4 (2.8) |
– |
||
Cavities on radiograph¶ | ||||||
Yes | 88 (46.3) | 24 (54.5) | 64 (43.8) | 1.39 | 0.83–2.34 | 0.21 |
No |
102 (53.7) |
20 (45.5) |
82 (56.2) |
Referent |
||
Sputum microscopy¶ | ||||||
Positive | 140 (73.7) | 39 (88.6) | 101(69.2) | 2.78 | 1.16–6.67 | 0.02 |
Negative |
50 (26.3) |
5 (11.4) |
45 (30.82) |
Referent |
||
Site of disease¶ | ||||||
Any pulmonary | 189 (99.5) | 44 (100) | 145 (99.3) | 0.59 | ||
Extrapulmonary only |
1 (0.5) |
0 |
1 (0.7) |
Referent |
||
Symptoms | ||||||
Yes | 122 (63.9) | 27 (61.4) | 95 (64.6) | 0.9 | 0.53–1.53 | 0.69 |
No |
69 (36.1) |
17 (38.6) |
52 (35.4) |
Referent |
||
Reasons for TB screening | ||||||
Symptomatic | 110 (57.6) | 27 (61.4) | 83 (56.4) | 1.1 | 0.62–1.79 | 0.85 |
Abnormal finding on radiograph | 6 (3.1) | 0 | 6 (4.1) | – | ||
Contact with TB patient | 2 (1.1) | 0 | 2 (1.4) | – | ||
Routine screening | 73 (38.2) | 17 (38.6) | 56 (38.1) | Referent |
*Values are no. (%) patients except as indicated. Cases were diagnosed at the Vladimir Regional TB Dispensary, Vladimir Region, Russia. MDR TB, multidrug-resistant TB. –, not applicable.
†Age and HIV status missing for 3 patients.
‡Wilcoxon rank sum test.
§Reasons for not working: retired, student, housewife, disabled.
¶Information was missing for 1 patient.
#Drug use data were missing for 2 patients.