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Volume 21, Number 3—March 2015
Dispatch

Reemergence of Murine Typhus in Galveston, Texas, USA, 2013

Lucas S. BlantonComments to Author , Rahat F. Vohra, Donald H. Bouyer, and David Walker
Author affiliations: University of Texas Medical Branch, Galveston, Texas, USA

Main Article

Table 2

Analysis of serosurvey samples found reactive to Rickettsia typhi by IFA and Western blotting, Galveston, Texas, 2013*

Sample Reciprocal IFA titers
Western blot analysis
R. typhi R. rickettsii R. typhi protein lysate (OmpB)† R. rickettsii protein lysate (OmpA‡)§
1 256 NR + –¶
2 128 NR +
3 128 NR +
4 128 NR +
5 256 NR +
6 128 NR +
7 1024 128 +
8 128 NR +

*Omp, outer membrane protein; NR, nonreactive at a titer of 1:128.
†Reactivity to the panrickettsial 135-kDa OmpB.
Reactivity to the spotted fever group 190-kDa OmpA.
§All serum samples reacted with R. rickettsii OmpB as described for spotted fever and typhus group OmpB antigens (10).
¶Bands corresponding to reactivity to OmpB but not OmpA confirms typhus group specificity.

Main Article

References
  1. Azad  AF, Radulovic  S, Higgins  JA, Noden  BH, Troyer  JM. Flea-borne rickettsioses: ecologic considerations. Emerg Infect Dis. 1997;3:31927. DOIPubMedGoogle Scholar
  2. Strandtmann  RW, Eben  DJ. A survey of typhus in rats and rat ectoparasites in Galveston, Texas. Tex Rep Biol Med. 1953;11:14451 .PubMedGoogle Scholar
  3. Basra  G, Berman  MA, Blanton  LS. Murine typhus: an important consideration for the nonspecific febrile illness. Case Rep Med. 2012;2012:134601 [cited 2014 Dec 12]. http://www.pubfacts.com/detail/23326268/Murine-typhus:-an-important-consideration-for-the-nonspecific-febrile-illness
  4. Blanton  LS, Walker  DH, Bouyer  DH. Rickettsiae and ehrlichiae within a city park: is the urban dweller at risk? Vector Borne Zoonotic Dis. 2014;14:16870. DOIPubMedGoogle Scholar
  5. Marrero  M, Raoult  D. Centrifugation-shell vial technique for rapid detection of Mediterranean spotted fever rickettsia in blood culture. Am J Trop Med Hyg. 1989;40:1979 .PubMedGoogle Scholar
  6. Philip  RN, Casper  EA, Ormsbee  RA, Peacock  MG, Burgdorfer  W. Microimmunofluorescence test for the serological study of Rocky Mountain spotted fever and typhus. J Clin Microbiol. 1976;3:5161 .PubMedGoogle Scholar
  7. Webb  L, Carl  M, Malloy  DC, Dasch  GA, Azad  AF. Detection of murine typhus infection in fleas by using the polymerase chain reaction. J Clin Microbiol. 1990;28:5304 .PubMedGoogle Scholar
  8. Regnery  RL, Spruill  CL, Plikaytis  BD. Genotypic identification of rickettsiae and estimation of intraspecies sequence divergence for portions of two rickettsial genes. J Bacteriol. 1991;173:157689 .PubMedGoogle Scholar
  9. Roux  V, Raoult  D. Phylogenetic analysis of members of the genus Rickettsia using the gene encoding the outer-membrane protein rOmpB (ompB). Int J Syst Evol Microbiol. 2000;50:144955. DOIPubMedGoogle Scholar
  10. Vishwanath  S. Antigenic relationships among the rickettsiae of the spotted fever and typhus groups. FEMS Microbiol Lett. 1991;81:3414. DOIPubMedGoogle Scholar
  11. Older  JJ. The epidemiology of murine typhus in Texas, 1969. JAMA. 1970;214:20117. DOIPubMedGoogle Scholar
  12. Dumler  JS, Taylor  JP, Walker  DH. Clinical and laboratory features of murine typhus in south Texas, 1980 through 1987. JAMA. 1991;266:136570. DOIPubMedGoogle Scholar
  13. Hill  EL, Ingraham  SC II. A study of murine typhus fever in Coffee County, Alabama. Public Health Rep. 1947;62:87581. DOIPubMedGoogle Scholar
  14. Eremeeva  ME, Karpathy  SE, Krueger  L, Hayes  EK, Williams  AM, Zaldivar  Y, Two pathogens and one disease: detection and identification of flea-borne rickettsiae in areas endemic for murine typhus in California. J Med Entomol. 2012;49:148594. DOIPubMedGoogle Scholar
  15. Adjemian  J, Parks  S, McElroy  K, Campbell  J, Eremeeva  ME, Nicholson  WL, Murine typhus in Austin, Texas, USA, 2008. Emerg Infect Dis. 2010;16:4127. DOIPubMedGoogle Scholar

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