Zika Virus Infection, Philippines, 2012
Maria Theresa Alera, Laura Hermann
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, Ilya A. Tac-An, Chonticha Klungthong, Wiriya Rutvisuttinunt, Wudtichai Manasatienkij, Daisy Villa, Butsaya Thaisomboonsuk, John Mark Velasco, Piyawan Chinnawirotpisan, Catherine B. Lago, Vito G. Roque, Louis R. Macareo, Anon Srikiatkhachorn, Stefan Fernandez, and In-Kyu Yoon
Author affiliations: Philippines-AFRIMS (Armed Forces Research Institute of Medical Sciences), Cebu City, Philippines (M.T. Alera, J.M. Velasco, C.B. Lago); University of Toronto, Toronto, Ontario, Canada (L. Hermann); AFRIMS, Bangkok, Thailand (L. Hermann, C. Klungthong, W. Rutvisuttinunt, W. Manasatienkij, B. Thaisomboonsuk, P. Chinnawirotpisan, L.R. Macareo, S. Fernandez, I.-K. Yoon); Cebu City Health Department, Cebu City (I.A. Tac-An, D. Villa); Department of Health, Manila, Philippines (V.G. Roque, Jr.); University of Massachusetts Medical School, Worcester, Massachusetts, USA (A. Srikiatkhachorn)
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Figure
Figure. Maximum-likelihood phylogenetic tree of fragments of Zika virus was determined using the general time-reversible plus gamma distribution plus invariable site model with 13 reference Zika virus strains from GenBank. The contig sequence, obtained from de novo assembly and blastn (http://blast.ncbi.nlm.nih.gov/Blast.cgi?PROGRAM=blastn&PAGE_TYPE=BlastSearch&LINK_LOC=blasthome), of the Philippines isolate from 2012 (GenBank accession no. KM851038; bold font) was analyzed against 8 reference strains from Africa (GenBank accession nos. KF268948, KF268949, KF268950, LC002520, AY632535, NC012532, HQ234500, HQ234501) and 5 reference strains from Asia (GenBank accession nos. KJ776791, JN860885, EU545988, HQ234499, KF993678). The year of collection is unknown for several strains from Africa. Bootstrap values >70 are indicated at nodes. Scale bar indicates nucleotide substitutions per site. The drawing is not to scale.
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