Volume 21, Number 7—July 2015
Ebola Virus Stability on Surfaces and in Fluids in Simulated Outbreak Environments
|Condition||Temperature, °C||Relative humidity, %||Model†||r2||Virus log reduction time, d‡|
|Stainless steel||27||80||Y = −2.240X + 6.729||0.9798||0.45|
|Stainless steel||21||40||Y = −0.7829X + 6.564||0.8544||1.3|
|Plastic||27||80||Y = −2.205X + 7.008||0.9745||0.45|
|Plastic||21||40||Y = −0.5445X + 6.188||0.8303||1.8|
|Tyvek||27||80||Y = −1.599X + 6.939||0.9713||0.63|
|Tyvek||21||40||Y = −0.4631X + 6.709||0.8878||2.2|
|Drying human blood||27||80||Y = −0.6806X + 4.951||0.8724||1.5|
|Drying human blood||21||40||Y = −0.6917X + 4.828||0.9037||1.5|
|Liquid human blood||27||NA||Y = −0.1148X + 4.651||0.2892||8.7|
|Liquid human blood||21||NA||Y = −0.05000X + 4.231||0.05293||20|
|Water||27||NA||Y = −1.133X + 4.483||0.9607||0.88|
|Water||21||NA||Y = −0.5694X + 4.201||0.9139||1.8|
*NA, not applicable.
†Y, log10 50% tissue culture infectious dose/mL; X, days.
‡In hospital conditions, virus titer on steel was reduced significantly faster than on plastic (p = 0.004) and on Tyvek (p<0.0001), but there was no significant difference in reduction between Tyvek and plastic (p = 0.13). In tropical conditions, there was no significant difference in virus titer reduction on steel and on plastic (p = 0.78). However, virus decayed more slowly on Tyvek than on steel (p<0.0001) and on plastic (p<0.0001). There was no significant difference in reduction rate in virus titer in drying human blood in hospital or tropical conditions (p = 0.92). Stability of virus in liquid blood did not fit a linear regression model. Virus was reduced significantly faster at 27°C than in water at 21°C (p = 0.0001).
1These authors contributed equally to this article.