Volume 21, Number 8—August 2015
Geographic Distribution and Expansion of Human Lyme Disease, United States
|Location, period||No. counties||Relative risk, range†||Average annual incidence, range‡||No. counties added to high-incidence status||No. counties removed from high- incidence status|
*In the first period, 4 counties in the southeastern United States met high-incidence criteria but are not included in the geographic focus–specific data. NA, not applicable.
†Relative risk is observed number of cases over a period divided by expected number of cases for the population at risk (4). For this analysis, high-incidence counties had a relative risk of >2.0.
‡Incidence is reported cases per 100,000 residents per year; population used was average population at risk during a period (US census data for midpoint of each period).
- Stanek G, Wormser GP, Gray J, Strle F. Lyme borreliosis. Lancet. 2012;379:461–73. DOIPubMedGoogle Scholar
- Steere AC, Coburn J, Glickstein L. The emergence of Lyme disease. J Clin Invest. 2004;113:1093–101. DOIPubMedGoogle Scholar
- Adams DA, Jajosky RA, Ajani U, Kriseman J, Sharp P, Onwen DH, et al. Summary of notifiable diseases—United States, 2012. MMWR Morb Mortal Wkly Rep. 2014;61:1–121.PubMedGoogle Scholar
- National Notifiable Diseases Surveillance System (NNDSS). Lyme disease (Borrelia burgdorferi). Case definitions [cited 2014 Oct 20]. http://wwwn.cdc.gov/nndss/script/conditionsummary.aspx?CondID=100
- Kulldorff M. SaTScan: software for the spatial, temporal, and space-time scan statistics. 2011 [cited 2013 Mar15]. http://www.satscan.org
- Connally NP, Ginsberg HS, Mather TN. Assessing peridomestic entomological factors as predictors for Lyme disease. J Vector Ecol. 2006;31:364–70. DOIPubMedGoogle Scholar
- Pepin KM, Eisen RJ, Mead PS, Piesman J, Fish D, Hoen AG, Geographic variation in the relationship between human Lyme disease incidence and density of infected host-seeking Ixodes scapularis nymphs in the eastern United States. Am J Trop Med Hyg. 2012;86:1062–71. DOIPubMedGoogle Scholar
- Chen H, White DJ, Caraco TB, Stratton HH. Epidemic and spatial dynamics of Lyme disease in New York State, 1990–2000. J Med Entomol. 2005;42:899–908.PubMedGoogle Scholar
- Frank C, Fix AD, Pena CA, Strickland GT. Mapping Lyme disease incidence for diagnostic and preventive decisions, Maryland. Emerg Infect Dis. 2002;8:427–9. DOIPubMedGoogle Scholar
- Bacon RM, Kugeler KJ, Mead PS. Surveillance for Lyme disease—United States, 1992–2006. MMWR Surveill Summ. 2008;57:1–9.PubMedGoogle Scholar
- Waller LA, Goodwin BJ, Wilson ML, Ostfeld RS, Marshall SL, Hayes EB. Spatio-temporal patterns in county-level incidence and reporting of Lyme disease in the northeastern United States, 1990–2000. Environ Ecol Stat. 2007;14:83–100. DOIGoogle Scholar
- Kitron U, Kazmierczak J. Spatial analysis of the distribution of Lyme disease in Wisconsin. Am J Epidemiol. 1997;145:558–66. DOIPubMedGoogle Scholar
- Eisen RJ, Lane RS, Fritz CL, Eisen L. Spatial patterns of Lyme disease risk in California based on disease incidence data and modeling of vector-tick exposure. Am J Trop Med Hyg. 2006;75:669–76.PubMedGoogle Scholar
- Teutsch SM, Churchill RE, editors. Principles and practices of public health surveillance. 2nd ed. New York: Oxford; 2000.
- Wormser GP, Masters E, Nowakowski J, McKenna D, Holmgren D, Ma K, Prospective clinical evaluation of patients from Missouri and New York with erythema migrans-like skin lesions. Clin Infect Dis. 2005;41:958–65. DOIPubMedGoogle Scholar