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Volume 22, Number 1—January 2016
Dispatch

Asymptomatic Lymphogranuloma Venereum in Men who Have Sex with Men, United Kingdom

Cara Saxon, Gwenda HughesComments to Author , Catherine Ison, and for the UK LGV Case-Finding Group
Author affiliations: Author affiliation: Public Health England, London, UK

Main Article

Table 1

Descriptive, univariable, and multivariable analysis of patients diagnosed with symptomatic versus nonsymptomatic LGV CT infection among men who have sex with men, by demographic and behavioral characteristics, United Kingdom*

Patient characteristics
No. (%) or median [IQR]

Univariable analysis

Multivariable analysis†
All CT
Non-LGV CT
LGV CT
OR (95% CI)
p value
OR (95% CI)
p value
All patients
713 (100)
647 (90.7)
66 (9.3)
ND
ND
ND
ND
Clinic location, n = 713
London 563 (79.0) 512 (79.1) 51 (77.3) 1 0.73
Manchester 85 (11.9) 75 (11.6) 10 (15.2) 1.34 (0.65–2.75)
Brighton 42 (5.9) 38 (5.9) 4 (6.1) 1.06 (0.36–3.08)
Glasgow‡
23 (3.2)
22 (3.4)
1 (1.5)






Infection site, n = 710
Nonrectal 221 (31.1) 217 (33.7) 4 (6.1) 1 1
Rectal
489 (68.9)
427 (66.3)
62 (93.9)

7.83 (2.81–21.82)
<0.001

10.08 (3.37–30.17)
<0.001
Multiple infection sites, n = 713
No 641 (89.9) 581 (89.8) 60 (90.9) 1
Yes
72 (10.1)
66 (10.2)
6 (9.1)

0.89 (0.37–2.15)
0.8



Symptoms present, n = 650
No 453 (69.7) 438 (73.6) 15 (27.3) 1 1
Yes
197 (30.3)
157 (26.4)
40 (72.7)

7.93 (4.20–14.99)
<0.001

13.33 (6.53–27.21)
<0.001
Age, y, n = 710 33 [27–42] 33 [27–42] 39 [33–46]
18–24 108 (15.2) 106 (16.5) 2 (3.0) 1 0.002
25–34 276 (38.9) 258 (40.1) 18 (27.3) 3.72 (0.85–16.31)
35–44 192 (27.0) 166 (25.8) 26 (39.4) 7.92 (1.84–34.15)
>44
134 (18.9)
114 (17.7)
20 (30.3)

9.11 (2.08–39.93)




Ethnicity, n = 603
White 480 (79.6) 432 (79.3) 48 (82.8) 1 0.17
Black or Black 
British 28 (4.6) 27 (5) 1 (1.7) 0.33 (0.44–2.51)
Mixed 27 (4.5) 27 (5) 0 NP
Asian and Asian 
British 21 (3.5) 21 (3.9) 0 NP
Other ethnic groups 23 (3.8) 19 (3.5) 4 (6.9) 1.89 (0.62–5.80)
Unknown
24 (4)
19 (3.5)
5 (8.6)

2.37 (0.85–6.63)




HIV status, n = 603
Negative 367 (60.9) 350 (64.2) 17 (29.3) 1 1
Positive
236 (39.1)
195 (35.8)
41 (70.7)

4.33 (2.40–7.82)
<0.001

3.63 (1.80–7.32)
<0.001
No. sexual partners in previous 3 mo, n = 635
No. partners 3 [1–5] 3 [1–5] 3 [1–8]
0–1 169 (26.6) 153 (26.3) 16 (29.6) 1 0.26
2–5 321 (50.6) 299 (51.5) 22 (40.7) 0.66 (0.34–1.31)
>6
145 (22.8)
129 (22.2)
16 (29.6)

1.13 (0.54–2.36)




Concurrent sexually transmitted infection, n = 631
No 451 (71.5) 406 (71) 45 (76.3) 1
Yes
180 (28.5)
166 (29)
14 (23.7)

0.76 (0.41–1.42)
0.39



STI within previous 12 mo, n = 594
No 469 (79) 435 (80.3) 34 (65.4) 1
Yes 125 (21) 107 (19.7) 18 (34.6) 2.15 (1.17–3.96) 0.01

*n values indicate number of patients for which data were available in each category. CT, Chlamydia trachomatis; LGV, lymphogranuloma venereum; IQR, interquartile range; OR, odds ratio; ND, no data were available; NP, not performed. Blank cells indicate not applicable.
†Multivariable analysis adjusted for age and location.
‡Glasgow patients were excluded from all univariable and multivariable analyses because they do not routinely report to the Genitourinary Medicine Clinic Activity Dataset.

Main Article

1Additional members of the UK LGV Case-Finding Group who contributed to data collection, analysis, and manuscript review are listed at the end of this article.

Page created: December 18, 2015
Page updated: December 18, 2015
Page reviewed: December 18, 2015
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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