Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 22, Number 11—November 2016
Dispatch

Staphylococcus aureus Colonization and Long-Term Risk for Death, United States

Angelico MendyComments to Author , Edgar R. Vieira, Ahmed N. Albatineh, and Janvier Gasana
Author affiliations: University of Iowa, Iowa City, Iowa, USA (A. Mendy); Florida International University, Miami, Florida, USA (E.R. Vieira, J. Gasana); Kuwait University, Kuwait City, Kuwait (A.N. Albatineh)

Main Article

Table 2

Cox proportional hazards regression for Staphylococcus aureus colonization and long-term mortality, United States*

Exposure variable‡ No. deaths No. patients Unadjusted
 Model 1
 Model 2
HR† (95% CI) p value HR† (95% CI)§ p value HR† (95% CI)¶ p value
S. aureus colonization
No S. aureus 1,051 7,794 1 (referent) 1 (referent) 1 (referent)
MSSA 279 2,668 0.82 (0.68–0.98) 0.035 1.03 (0.85–1.24) 0.79 1.06 (0.88–1.27) 0.52
MRSA 41 136 2.40 (1.56–3.69) <0.001 1.54 (1.06–2.34) 0.026 1.38 (0.88–2.17) 0.15
MRSA SCCmec II 36 83 3.38 (2.00–5.72) <0.001 1.42 (0.88–2.26) 0.14 1.40 (0.87–2.24) 0.16
MRSA SCCmec IV
 5
 53
 1.07 (0.37–3.12)
 0.9
2.05 (0.60–7.03)
 0.25
1.96 (0.55–6.92)
 0.29
In colonized participants
MSSA 279 2,668 1 (referent) 1 (referent) 1 (referent)
MRSA 41 136 2.90 (1.92–4.40) <0.001 1.48 (0.94–2.32) 0.09 1.27 (0.76–2.13) 0.35
MRSA SCCmec II 36 83 4.05 (2.42–6.79) <0.001 1.36 (0.84–2.21) 0.2 1.17 (0.66–2.08) 0.58
MRSA SCCmec IV 5 53 1.30 (0.44–3.84) 0.63 1.90 (0.54–6.64) 0.3 1.97 (0.58–6.70) 0.26

*HR, hazard ratio; MSSA, methicillin-susceptible S. aureus; MRSA, methicillin-resistant S. aureus; SCCmec: staphylococcal cassette chromosome mec.
†Generated by using Cox proportional hazards regression.
‡Categorized into no S. aureus colonization (0), MSSA colonization (1) and MRSA colonization (2), to generate hazard ratios for MSSA colonization (1) and MRSA colonization (2) in reference to no S. aureus colonization (0). In the analysis by SCCmec types, exposure was categorized into: no S. aureus colonization (0), MSSA colonization (1), MRSA SCCmec II (2), and MRSA SCCmec IV (3) and hazard ratios for MRSA SCCmec II (2), and MRSA SCCmec IV were reported. In colonized participants, the analysis was repeated with MSSA colonization being the reference category.
§Adjusted for age, sex, race/ethnicity, and Poverty Income Ratio.
¶Adjusted for age, sex, race/ethnicity, poverty Income ratio, smoking, body mass index, and co-morbidities (asthma, diabetes, hypertension, cardiovascular diseases, stroke, liver disease, and cancer).

Main Article

Page created: October 19, 2016
Page updated: October 19, 2016
Page reviewed: October 19, 2016
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external