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Volume 22, Number 11—November 2016

Shigella flexneri with Ciprofloxacin Resistance and Reduced Azithromycin Susceptibility, Canada, 2015

Christiane GaudreauComments to Author , Pierre A. Pilon, Gilbert Cornut, Xavier Marchand-Senecal, and Sadjia Bekal
Author affiliations: Centre Hospitalier de l’Université de Montréal–Hôpital Saint-Luc, Montreal, Quebec, Canada (C. Gaudreau, G. Cornut, X. Marchand-Senecal); Université de Montréal, Montreal (C. Gaudreau, P.A. Pilon, G. Cornut, X. Marchand-Senecal, S. Bekal); Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l’île-de-Montreal, Montreal (P.A. Pilon); Laboratoire de Santé Publique du Québec/Institut National de Santé Publique du Québec, Sainte-Anne-de-Bellevue, Quebec (C. Gaudreau, S. Bekal)

Main Article


Antimicrobial susceptibility of the Shigella flexneri,serotype 2a pulsovar 21, isolated in Montreal, Quebec, Canada, 2015*

Antimicrobial agent Disk diffusion, mm MIC, mg/L Interpretation
Ampicillin 6 ≥32 R
TMP/SMX 6 ≥320 R
Ciprofloxacin 12 ≥4 and 8 R
Nalidixic acid 6 NA R
Ceftriaxone 33 ≤0.25 S
Cefixime 26 0.25 S
Azithromycin† 6 >256 NS
Tetracycline 6 32 R
Chloramphenicol NA >256 R
Amoxicillin-clavulanic acid 14 16 I
Ertapenem NA ≤0.5 S
*I, intermediate; NA, not available; NS, nonsusceptible; R, resistant; S, susceptible; TMP/SMX, trimethoprim/sulfamethoxazole.
†Azithromycin epidemiologic cutoff values for wild-type (MIC ≤8 mg/L) and non–wild-type (MIC ≥16 mg/L) Shigella flexneri (2) and the susceptibility and resistance breakpoints for the other 11 antimicrobial agents were CLSI Enterobacteriaceae breakpoints (2).

Main Article

Page created: October 19, 2016
Page updated: October 19, 2016
Page reviewed: October 19, 2016
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