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Volume 22, Number 11—November 2016
Letter

HIV/Hepatitis C Virus Co-infection among Adults Beginning Antiretroviral Therapy, Malawi

Münevver DemirComments to Author , Sam Phiri, Rolf Kaiser, Thom Chaweza, Florian Neuhann, Hannock Tweya, Gerd Fätkenheuer, and Hans-Michael Steffen
Author affiliations: University Hospital of Cologne, Cologne, Germany (M. Demir, R. Kaiser, G. Fätkenheuer, H.-M. Steffen); Lighthouse Clinic, Lilongwe, Malawi (S. Phiri, T. Chaweza, H. Tweya); Institute of Public Health, University Hospital of Heidelberg, Heidelberg, Germany (F. Neuhann) ; German Centre for Infection Research, Cologne, (G. Fätkenheuer)

Main Article

Table

Characteristics of HIV-positive adults with HIV/HCV co-infection, Malawi*

Characteristic HIV-positive and HCV antibody–negative patients, n = 222 HIV-positive and HCV-antibody–positive patients, n = 5
Age, y 36.1 (30.5–41.5) 34.5 (24.8–50.2)
Sex, M/F 88/134 (40/60) 2/3 (40/60)
Weight, kg, n = 167 59.1 (52.7–66.7) 59.6 (55.9–68.7)
Height, cm, n = 170 157.0 (151.0–165.0) 159.5 (151.0–167.0)
Quantitative HIV RNA [<40] × 103, copies/mL, n = 205 44.43 (12.09–158.96) 30.87 (21.14–95.38)
History of blood transfusion 21 (9) 1(20)
History of jaundice 2 (1) 0
eGFR mL/min/1,73 qm, n = 194 96.0 (79.0–110.0) 91.0 (88.0–94.0)
ALT [7–35], IU/L, n = 183 23.3 (14.9–33.4) 15.6 (13.2–22.5)
AST [≤38], IU/L, n = 183 31.7 (23.0–42.4) 31.9 (23.2–43.7)
Total bilirubin level [≤1.3], mg/dL, n = 185 0.30 (0.20–0.45) 0.26 (0.20–0.48)
Platelet count [122–330] × 109/L, n = 214 226 (181–293) 283 (160–320)
Hemoglobin level [10.9–17.3], g/dL, n = 215 12.4 (10.8–13.7) 13.3 (11.8–15.1)
Leukocyte count [2,800–8,400], cells/µL, n = 213 4,400 (3,500–5,400) 3,900 (2,700–6,600)
CD4 cell count, cells/µL, n = 139 284 (101–421) 319 (189–449)

*Values are given as total no. (%) or as median with interquartile range for the HCV antibody–negative study population and median with range for the HCV antibody–positive study population, respectively. Reference values are given in brackets. Number of missing values for the HCV-antibody negative patients ranged from 88 to 3, indicated by differing patient numbers in stub column. ALT, alaninine aminotransferase; AST, aspartate aminotransferase; eGFR, estimated glomerular filtration rate; HCV, hepatitis C virus.

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Page created: October 19, 2016
Page updated: October 19, 2016
Page reviewed: October 19, 2016
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