Volume 22, Number 2—February 2016
Research
Randomized Controlled Trial of Hospital-Based Hygiene and Water Treatment Intervention (CHoBI7) to Reduce Cholera
Table 2
Evaluation of intervention efficacy to reduce Vibrio cholerae infection among household contacts of cholera patients during the intervention period (visits 2–5), Dhaka, Bangladesh, June 2013–November 2014
Household contact characteristic | No. (%) contacts |
Odds ratio (95% CI) | p value* | |
---|---|---|---|---|
Control arm | Intervention arm | |||
Culture results available | 160 (100) | 160 (100) | – | – |
Negative for V. cholerae infection at baseline | 148 (93) | 140 (88) | 1.15 (0.88–1.51) | 0.30 |
Initial V. cholerae infections during the intervention period | 20 (14) | 10 (7) | 0.50 (0.21–1.18) | 0.11 |
Initial symptomatic V. cholerae infections during intervention period† | 8 (5) | 0 | 0.00 (0–0.623)‡ | 0.006§ |
*Calculated with logistic regression model by using generalized estimating equations to account for clustering within study households.
†Symptomatic infection defined as a V. cholerae–infected household contact with diarrhea or vomiting in the past 48 hours.
‡To calculate exact 95% CIs, an algorithm was used to invert household-level test statistics.
§Fisher exact test calculated at the household level.