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Volume 22, Number 4—April 2016
Dispatch

Adenovirus Type 7 Pneumonia in Children Who Died from Measles-Associated Pneumonia, Hanoi, Vietnam, 2014

Le Thanh Hai, Hoang Ngoc Thach, Ta Anh Tuan, Dao Huu Nam, Tran Minh Dien, Yuko Sato, Toshio Kumasaka, Tadaki Suzuki, Nozomu Hanaoka, Tsuguto Fujimoto, Harutaka Katano, Hideki Hasegawa, Shoji Kawachi, and Noriko NakajimaComments to Author 
Author affiliations: The National Hospital of Pediatrics, Hanoi, Vietnam (L.T. Hai, H.N. Thach, T.A. Tuan, D.H. Nam, T.M. Dien); National Institute of Infectious Diseases, Tokyo, Japan (Y. Sato, T. Suzuki, N. Hanaoka, T. Fujimoto, H. Katano, H. Hasegawa, N. Nakajima); Japanese Red Cross Medical Center, Tokyo (T. Kumasaka); Tomakomai City Hospital, Tomakomai, Japan (S. Kawachi)

Main Article

Table 1

Clinical and laboratory characteristics of 16 children who died from measles-associated pneumonia in a pediatric intensive care unit, National Hospital of Pediatrics, Hanoi, Vietnam, February–June 2014*

Pt. no.
 Age, mo/sex
 Days from onset to
 CD4/μL (CD4 %)
 MEAS IgM†
 Laboratory test results (type of test)
PICU admission
 Death
 NPA/TLA (culture)
 Blood (rPCR)
 AdV
TLA (PCR)
 CMV/mL blood (rPCR)
1 6/M 5 6 530 (28) + – – ND ND
2 8/M 4 6 538 (19) + – – – 1.90 × 105
3 14/F 9 12 754 (15) + – – ND ND
4 12/M 6 14 714 (31) + – – + ND
5 8/F 15 17 341 (37) + – ND + –
6 16/F 16 18 120 (34) – – – + –
7 10/M 22 27 793 (47) + Acinetobacter spp. Acinetobacter spp. + 6.72 × 104
8 8/M 28 30 1,084 (26) + – – ND ND
9 15/M 10 14 2,578 (52) + – Candida tropicalis,
C. parapsilosis + 1.10 × 104
10 4/M 10 15 947 (46) + – Klebsiella pneumoniae, K. oxytoca, Enterobacter cloacae, E. aerogenes + –
11 9/F 16 20 372 (29) + – C. albicans + 1.10 × 104
12 7/F 11 27 472 (21) – – Pseudomonas aeruginosa,
Enterococcus faecalis, Stenotrophomonas maltophilia – –
13 5/F 5 21 202 (22) + – – – 2.03 × 104
14 4/M 5 24 326 (12) + – – ND 4.79 × 105
15 7/M 8 25 1,732 (49) + K. pneumoniae Staphylococcus haemolyticus + 3.20 × 103
16 15/F 5 10 ND + Staphylococcus aureus – ND ND

*+, positive; –, negative; AdV, adenovirus; CMV, cytomegalovirus; MEAS, measles virus, ND, not done; NPA, nasopharyngeal aspirate; Pt, patient; PICU, pediatric intensive care unit; rPCR, real-time PCR; TLA, trachea lavage aspirate.
†Specimens from patients 6 and 12 were positive for measles virus RNA.

Main Article

Page created: March 16, 2016
Page updated: March 16, 2016
Page reviewed: March 16, 2016
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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