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Volume 22, Number 6—June 2016
Research

Use of Population Genetics to Assess the Ecology, Evolution, and Population Structure of Coccidioides

Marcus M. Teixeira and Bridget M. BarkerComments to Author 
Author affiliations: Translational Genomics Research Institute, Flagstaff, Arizona, USA (M.M. Teixeira, B.M. Barker); Northern Arizona University, Flagstaff (B.M. Barker); University of Arizona, Tucson, Arizona, USA (B.M. Barker)

Main Article

Table 2

Principal coordinates analysis results indicating percentage of variation among Coccidioides populations, Arizona, USA

Value Axis
1 2 3
% Variation
 93.92
 3.95
 1.44
Total eigenvalue 1.202 0.051 0.018
PHOENIX 0.491 −0.061 0.009
AZSOIL 0.498 −0.018 0.009
TUCSON 0.213 −0.012 −0.103
SJV −0.552 0.089 −0.023
SDMX −0.552 −0.098 0.022
MEXICO 0.162 0.048 0.081
TXSA 0.179 0.163 −0.001

*PHOENIX represents primarily Coccidioides posadasii human clinical isolates from Yuma and Phoenix, Arizona. AZSOIL represents primarily environmental and veterinary clinical C. posadasii isolates from Arizona. TUCSON represents primarily human clinical C. posadasii isolates from Tucson, Arizona. SJV represents primarily C. immitis human clinical isolates from Bakersfield, California. SDMX represents primarily C. immitis human clinical isolates from San Diego, California, and Mexico. MEXICO represents primarily human clinical C. posadasii isolates from Mexico. TXSA represents primarily human clinical C. posadasii isolates from Texas, Brazil, Argentina, and Venezuela. Axis 1 explains 93.92% of the genetic variation among the populations, which is due mainly to separation of C. immitis (SJV and SDMX) from C. posadasii. Axis 2 suggests gene flow between SJV, MEXICO, and TXSA. Axis 3 indicates that the TUCSON population contains unique genetic signatures.

Main Article

Page created: May 16, 2016
Page updated: May 16, 2016
Page reviewed: May 16, 2016
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