Volume 22, Number 6—June 2016
Dispatch
Prevalence of Nontuberculous Mycobacterial Pulmonary Disease, Germany, 2009–2014
Felix C. Ringshausen
, Dirk Wagner, Andrés de Roux, Roland Diel, David Hohmann, Lennart Hickstein, Tobias Welte, and Jessica Rademacher
, Dirk Wagner, Andrés de Roux, Roland Diel, David Hohmann, Lennart Hickstein, Tobias Welte, and Jessica Rademacher
Table 1
Prevelance of nontuberculous mycobacterial pulmonary disease, stratified by age, sex, and year; Germany, 2009–2014*
| Characteristic | 2009 | 2010 | 2011 | 2012 | 2013 | 2014 |
|---|---|---|---|---|---|---|
| Population of Germany, total no. | 81,802,257 | 81,751,602 | 80,327,900 | 80,523,746 | 80,767,463 | 81,197,537 |
| Mean age, y | 43.4 | 43.7 | 43.9 | 44.1 | 44.2 | 44.3 |
| Sex ratio, F:M | 1.04 | 1.04 | 1.05 | 1.05 | 1.04 | 1.04 |
| No. persons insured by SHI (% Germany population) | 70,011,718 (85.6) | 69,803,236 (85.4) | 69,637,277 (86.7) | 69,704,323 (86.6) | 69,861,165 (86.5) | 70,289,808 (86.6) |
| No. persons in study sample (% Germany population) | 3,646,060 (4.5) | 3,708,501 (4.5) | 3,985,981 (5.0) | 3,982,716 (4.9) | 3,977,676 (4.9) | 3,793,331 (4.7) |
| Mean age, y | 44.0 | 44.1 | 43.7 | 44.0 | 44.3 | 45.1 |
| Sex ratio, F:M | 1.03 | 1.03 | 1.04 | 1.04 | 1.04 | 1.04 |
| No. case-patients with NTM-PD | 85 | 96 | 106 | 106 | 104 | 126 |
| M, no. (% case-patients with NTM-PD) | 43 (50.6) | 50 (52.1) | 50 (47.2) | 60 (56.6) | 49 (47.1) | 63 (50.0) |
| F, no. (% case-patients with NTM-PD) | 42 (49.4) | 46 (47.9) | 56 (52.8) | 46 (43.4) | 55 (52.9) | 63 (50.0) |
| Outpatient care, no. (% case-patients with NTM-PD) | 74 (87.1) | 79 (82.3) | 80 (75.5) | 88 (83.0) | 85 (81.7) | 104 (82.5) |
| Hospital care, no. (% case-patients with NTM-PD) | 20 (23.5) | 28 (29.2) | 34 (32.1) | 25 (23.6) | 37 (35.6) | 38 (30.2) |
| Outpatient and hospital care, no. (% Case-patients with NTM-PD) | 9 (10.6) | 11 (11.5) | 8 (7.5) | 7 (6.6) | 18 (17.3) | 16 (12.7) |
| Hospital but no outpatient care in the same year, no. (% case-patients who had hospital care) | 11 (55.8) | 17 (60.7) | 26 (76.5) | 18 (72.0) | 19 (51.4) | 22 (57.9) |
| Mean age of case-patients with NTM-PD, y (SD) | 60.3 (20.0) | 57.3 (22.2) | 55.0 (23.8) | 55.5 (25.4) | 59.7 (22.6) | 61.0 (20.4) |
| M | 58.7 (20.1)† | 55.3 (21.3)† | 57.6 (20.0)† | 55.2 (25.3)† | 54.8 (24.6)‡ | 58.2 (19.3)† |
| F | 62.1 (20.0) | 59.4 (23.2) | 52.7 (26.7) | 56.0 (25.7) | 64.1 (19.8) | 63.7 (21.2) |
| Prevalence, rate/100,000 population, total (95% CI) | 2.3 (1.87–2.87) | 2.6 (2.11–3.15) | 2.7 (2.19–3.20) | 2.7 (2.19–3.21) | 2.6 (2.15–3.16) | 3.3 (2.78–3.94) |
| M | 2.4 (1.76–3.20) | 2.8 (2.06–3.59) | 2.6 (1.92–3.34) | 3.1 (2.36–3.92) | 2.5 (1.88–3.29) | 3.4 (2.63–4.31) |
| F | 2.3 (1.65–3.03) | 2.4 (1.81–3.22) | 2.8 (2.10–3.56) | 2.3 (1.68–3.0) | 2.7 (2.07–3.51) | 3.3 (2.53–4.14) |
| Projected total number of case-patients with NTM-PD in Germany | 1,907 | 2,116 | 2,136 | 2,143 | 2,112 | 2,697 |
*SHI, statutory health insurance; NTM-PD, nontuberculous mycobacterial pulmonary disease.
†Mean age was not significantly different among male and female patients: 2009, p = 0.44; 2010, p = 0.37; 2011, p = 0.28; 2012, p = 0.87; 2014, p = 0.13.
‡p = 0.038 for mean age between male and female patients.
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