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Volume 22, Number 6—June 2016
CME ACTIVITY - Synopsis

Human Infection with Influenza A(H7N9) Virus during 3 Major Epidemic Waves, China, 2013–2015

Peng Wu1, Zhibin Peng1, Vicky J. Fang, Luzhao Feng, Tim K. Tsang, Hui Jiang, Eric H.Y. Lau, Juan Yang, Jiandong Zheng, Ying Qin, Qiao Sun, Gabriel M. Leung, Sheng WeiComments to Author , and Benjamin J. Cowling
Author affiliations: World Health Organization Collaborating Centre for Infectious Disease Epidemiology and Control, School of Public Health, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China (P. Wu, V.J. Fang, T.K. Tsang, E.H.Y. Lau, G.M. Leung, B.J. Cowling); Division of Infectious Disease, Key Laboratory of Surveillance and Early-warning on Infectious Disease, Chinese Center for Disease Control and Prevention, Beijing, China (Z. Peng, L. Feng, H. Jiang, J. Yang, J. Zheng, Y. Qin, Z. Li, H. Yu)

Main Article

Table 2

Comparison of risk of death among patients with laboratory-confirmed influenza A(H7N9) virus infection detected in 3 epidemic waves, China, 2013–2015

Characteristic Laboratory-confirmed H7N9 deaths, adjusted odds ratio (95% CI)
Model 1 Model 2
Wave
1A 4.88 (1.64–14.53) 5.07 (1.67–15.46)
1B 1.00 1.00
2 2.39 (1.46–3.91) 3.48 (2.00–6.06)
3
 3.93 (2.30–6.72)
 4.84 (2.66–8.80)
Age group, y
0–15 0.56 (0.05–5.78) 0.50 (0.05–5.43)
16–59 1.00 1.00
60–74 2.05 (1.38–3.04) 2.09 (1.34–3.26)
>75
 2.88 (1.75–4.74)
 2.49 (1.44–4.30)
Sex
F 1.00 1.00
M
 1.00 (0.68–1.46)
 0.94 (0.61–1.45)
Underlying medical conditions
No underlying medical disorder 1.00 1.00
>1 underlying medical condition*
 1.28 (0.88–1.84)
 1.22 (0.82–1.81)
Residence
Residence in a provincial capital or municipality – 1.00
Residence in other cities§ – 0.52 (0.30–0.89)
Rural residence
 –
 0.53 (0.31–0.91)
Onset to final hospital admission, d
0–4 – 1.00
5–7 – 1.21 (0.77–1.90)
>7 – 1.19 (0.72–1.95)

*Only underlying medical disorders associated with a high risk for influenza complications were counted here, including chronic respiratory disease, asthma, chronic cardiovascular disease, diabetes, chronic liver disease, chronic kidney disease, immunosuppressed status, and neuromuscular disorders.

Main Article

1These authors contributed equally to this article.

Page created: May 12, 2016
Page updated: May 12, 2016
Page reviewed: May 12, 2016
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