Figure. Ebola virus inactivation results as tested in BALB/c mouse model. A) Survival in animal groups tested with samples inactivated by guanidinium isothiocyanate buffers. AVL140, 140 µL Buffer AVL (QIAGEN, Valencia, CA, USA) + 560 µL sample; AVL100, 100 µL Buffer AVL + 600 µL sample; RLT600, 600 µL Buffer RLT (QIAGEN) treatment of cells; RLT800, 800 µL Buffer RLT treatment of cells; + ethanol, after a Buffer AVL or Buffer RLT inactivation contact time of 10 min, addition of 100% or 70% ethanol, respectively, for an additional 20 min of contact time. B) Survival in animal groups tested with samples inactivated by fixative or detergent buffers. For all test groups, n = 15; for all control groups, n = 5.