Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 22, Number 7—July 2016
Dispatch

Effective Chemical Inactivation of Ebola Virus

Elaine Haddock, Friederike Feldmann, and Heinz FeldmannComments to Author 
Author affiliations: National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA

Main Article

Figure

Ebola virus inactivation results as tested in BALB/c mouse model. A) Survival in animal groups tested with samples inactivated by guanidinium isothiocyanate buffers. AVL140, 140 µL Buffer AVL (QIAGEN, Valencia, CA, USA) + 560 µL sample; AVL100, 100 µL Buffer AVL + 600 µL sample; RLT600, 600 µL Buffer RLT (QIAGEN) treatment of cells; RLT800, 800 µL Buffer RLT treatment of cells; + ethanol, after a Buffer AVL or Buffer RLT inactivation contact time of 10 min, addition of 100% or 70% ethanol, respe

Figure. Ebola virus inactivation results as tested in BALB/c mouse model. A) Survival in animal groups tested with samples inactivated by guanidinium isothiocyanate buffers. AVL140, 140 µL Buffer AVL (QIAGEN, Valencia, CA, USA) + 560 µL sample; AVL100, 100 µL Buffer AVL + 600 µL sample; RLT600, 600 µL Buffer RLT (QIAGEN) treatment of cells; RLT800, 800 µL Buffer RLT treatment of cells; + ethanol, after a Buffer AVL or Buffer RLT inactivation contact time of 10 min, addition of 100% or 70% ethanol, respectively, for an additional 20 min of contact time. B) Survival in animal groups tested with samples inactivated by fixative or detergent buffers. For all test groups, n = 15; for all control groups, n = 5.

Main Article

Page created: July 09, 2018
Page updated: July 09, 2018
Page reviewed: July 09, 2018
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external