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Volume 22, Number 9—September 2016
Research

Feasibility of Using Convalescent Plasma Immunotherapy for MERS-CoV Infection, Saudi Arabia

Yaseen M. ArabiComments to Author , Ali H. Hajeer, Thomas Luke, Kanakatte Raviprakash, Hanan Balkhy, Sameera Johani, Abdulaziz Al-Dawood, Saad Al-Qahtani, Awad Al-Omari, Fahad Al-Hameed, Frederick G. Hayden1, Robert Fowler, Abderrezak Bouchama, Nahoko Shindo, Khalid Al-Khairy, Gail Carson, Yusri Taha, Musharaf Sadat, and Mashail Alahmadi
Author affiliations: King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, Riyadh, Saudi Arabia (Y.M. Arabi, A.H. Hajeer , H. Balkhy, S. Johani, A. Al-Dawood, S. Al-Qahtani, A. Bouchama, K. Al-Khairy, M. Sadat, M. Alahmadi); Naval Medical Research Center, Silver Spring, Maryland, USA (T. Luke, K. Raviprakash); Alfaisal University, Riyadh (A. Al-Omari); King Saud bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia (F. Al-Hameed); University of Virginia School of Medicine, Charlottesville, Virginia, USA (F.G. Hayden); University of Toronto, Toronto, Ontario, Canada (R. Fowler); World Health Organization, Geneva, Switzerland (N. Shindo); University of Oxford Centre for Tropical Medicine, Oxford, UK (G. Carson); King Abdulaziz Medical City, Al-Ahsa, Saudi Arabia (Y. Taha)

Main Article

Figure 2

Clinical and laboratory timeline for a Middle East respiratory coronavirus–infected patient with high ELISA, indirect immunofluorescent antibody (IFA), and microneutralization (MN) titers. The highest titers were measured while the patient had active infection and was critically ill. The ELISA optical density ratio and IFA and MN titers declined as the patient recovered. ICU, intensive care unit; rRT-PCR, real-time reverse transcription PCR; ward, hospital ward; −, negative; +, positive.

Figure 2. Clinical and laboratory timeline for a Middle East respiratory coronavirus–infected patient with high ELISA, indirect immunofluorescent antibody (IFA), and microneutralization (MN) titers. The highest titers were measured while the patient had active infection and was critically ill. The ELISA optical density ratio and IFA and MN titers declined as the patient recovered. ICU, intensive care unit; rRT-PCR, real-time reverse transcription PCR; ward, hospital ward; −, negative; +, positive.

Main Article

1This author is a member of ISARIC (the International Severe Acute Respiratory and Emerging Infection Consortium).

Page created: August 16, 2016
Page updated: August 16, 2016
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The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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